{Reference Type}: Journal Article {Title}: Relationship between COVID-19 and orofacial clefts. {Author}: Molnárová A;Fekiačová D;Záhumenský J;Rosoľanková M;Ujházy E;Dubovický M;Palenčár D; {Journal}: Gen Physiol Biophys {Volume}: 43 {Issue}: 4 {Year}: 2024 Jul {Factor}: 1.957 {DOI}: 10.4149/gpb_2024012 {Abstract}: The work presents the connection between the infection of COVID-19 during pregnancy and non-syndromic orofacial clefts (NSOFC). Aim of the study was to compare the incidence of COVID-19 disease during mother´s pregnancy between a group of the children with NSOFC and a control group of the children without NSOFC. COVID-19 was confirmed by polymerase chain reaction (PCR) test. The study showed significantly higher incidence of COVID-19 disease in the group of mothers who gave birth to a child with NSOFC in comparison to the group of mothers who gave birth to a child without NSOFC. Our results indicate the possible participation of the infection of COVID-19 in the formation of NSOFCs.