PDF(Pubmed)
Abstract：
UNASSIGNED: Iron deficiency is known to impair muscle function and reduce athletic performance, while vitamin D has been reported to induce iron deficiency. However, the mechanism underlying exercise-induced changes in iron metabolism and the involvement of vitamins in this mechanism are unclear. The present study examined changes in biological iron metabolism induced by continuous training and the effects of vitamin D on these changes.
UNASSIGNED: Diet, physical characteristics, and blood test data were collected from 23 female high school students in a dance club on the last day of each of a 2-month continuous training period and a 2-week complete rest periods.
UNASSIGNED: Serum hepcidin-25 levels were significantly lower during the training period than the rest period (p = 0.013), as were the red blood cell count, hemoglobin, and hematocrit (all p < 0.001). Serum erythropoietin was significantly higher (p = 0.001) during the training period. Significant positive correlations were observed between 25(OH)D levels and serum iron, serum ferritin, and transferrin saturation during the training period. Multiple regression analysis with serum 25(OH)D level as the dependent variable and serum ferritin and iron levels as independent variables during the training period revealed a significant association with serum ferritin.
UNASSIGNED: Continuous training may promote hemolysis and erythropoiesis, contributing to the suppression of hepcidin expression. The relationship between serum 25(OH)D and iron in vivo may be closely related to metabolic changes induced by the exercise load.
UNASSIGNED: Diet, physical characteristics, and blood test data were collected from 23 female high school students in a dance club on the last day of each of a 2-month continuous training period and a 2-week complete rest periods.
UNASSIGNED: Serum hepcidin-25 levels were significantly lower during the training period than the rest period (p = 0.013), as were the red blood cell count, hemoglobin, and hematocrit (all p < 0.001). Serum erythropoietin was significantly higher (p = 0.001) during the training period. Significant positive correlations were observed between 25(OH)D levels and serum iron, serum ferritin, and transferrin saturation during the training period. Multiple regression analysis with serum 25(OH)D level as the dependent variable and serum ferritin and iron levels as independent variables during the training period revealed a significant association with serum ferritin.
UNASSIGNED: Continuous training may promote hemolysis and erythropoiesis, contributing to the suppression of hepcidin expression. The relationship between serum 25(OH)D and iron in vivo may be closely related to metabolic changes induced by the exercise load.
摘要：
■已知缺铁会损害肌肉功能并降低运动表现，据报道，维生素D会导致铁缺乏。然而,运动引起的铁代谢变化和维生素参与这一机制的潜在机制尚不清楚.本研究检查了连续训练引起的生物铁代谢变化以及维生素D对这些变化的影响。
■饮食，物理特性,在两个月的连续训练期和两周的完整休息时间的最后一天，从舞蹈俱乐部的23名女高中生收集了血液测试数据。
■训练期间的血清铁调素-25水平显着低于休息期间（p=0.013），红细胞计数也是如此，血红蛋白,和血细胞比容（所有p<0.001）。在训练期间，血清促红细胞生成素显着升高（p=0.001）。25(OH)D水平与血清铁呈正相关,血清铁蛋白,和转铁蛋白饱和度在训练期间。在训练期间，以血清25（OH）D水平为因变量，血清铁蛋白和铁水平为自变量的多元回归分析显示，与血清铁蛋白存在显着关联。
■持续训练可能会促进溶血和红细胞生成，有助于hepcidin表达的抑制。体内血清25(OH)D与铁的关系可能与运动负荷引起的代谢变化密切相关。
■饮食，物理特性,在两个月的连续训练期和两周的完整休息时间的最后一天，从舞蹈俱乐部的23名女高中生收集了血液测试数据。
■训练期间的血清铁调素-25水平显着低于休息期间（p=0.013），红细胞计数也是如此，血红蛋白,和血细胞比容（所有p<0.001）。在训练期间，血清促红细胞生成素显着升高（p=0.001）。25(OH)D水平与血清铁呈正相关,血清铁蛋白,和转铁蛋白饱和度在训练期间。在训练期间，以血清25（OH）D水平为因变量，血清铁蛋白和铁水平为自变量的多元回归分析显示，与血清铁蛋白存在显着关联。
■持续训练可能会促进溶血和红细胞生成，有助于hepcidin表达的抑制。体内血清25(OH)D与铁的关系可能与运动负荷引起的代谢变化密切相关。
