Abstract：
Public health, personal/community health behaviors, health care delivery, and the scientific community have all been impacted by the COVID-19 pandemic and are consequently poised to consider substantial paradigm shifts that will enhance disease prevention and public health resilience. The current analysis compares the newly developed Lifestyle Health Index (LHI) to U.S. county-level COVID-19 vaccination, infection, and mortality rates. We linked Centers of Disease Control PLACES, the U.S. Community Profile Report, and Nationhood lab databases through common zip-code identifiers to determine the association between county-level LHI scores and COVID-19 outcomes and vaccination status against the backdrop of U.S. regions with distinct cultural phenotypes. There was a statistically significant relationship between a poor LHI, lower COVID-19 vaccination rates and higher COVID-19 infection and mortality rates. There were clear differences in outcomes across the U.S. regions, suggesting distinct regional cultural characteristics may significantly influence health behaviors and outcomes. In the U.S., a syndemic comprising unhealthy lifestyle, chronic disease, and COVID-19 resulted in unnecessary hospitalizations and deaths. Politicization of the pandemic, socioeconomic inequity and regional cultural values meaningfully contributed to the uneven distribution of poor outcomes during this syndemic. Components of the syndemic were avoidable and should not be repeated. Condensed Abstract: The unhealthy lifestyle - chronic disease - COVID-19 U.S. syndemic resulted in unnecessary hospitalizations and deaths. Politicization of the pandemic, socioeconomic inequity and regional cultural values meaningfully contributed to the uneven distribution of poor outcomes during this syndemic. Components of the syndemic were avoidable and should not be repeated.
摘要：
公共卫生,个人/社区健康行为，卫生保健服务，科学界都受到了COVID-19大流行的影响，因此准备考虑重大的范式转变，以增强疾病预防和公共卫生抵御能力。当前的分析将新开发的生活方式健康指数（LHI）与美国县级COVID-19疫苗接种进行了比较，感染,和死亡率。我们联系了疾病控制中心,美国社区概况报告,和国家实验室数据库，通过通用邮政编码标识符确定县级LHI评分与COVID-19结果和疫苗接种状态之间的关联，以在具有不同文化表型的美国地区为背景。差的LHI之间存在统计学上的显着关系，COVID-19疫苗接种率较低，COVID-19感染率和死亡率较高。美国各地区的结果存在明显差异，表明不同的区域文化特征可能会显著影响健康行为和结果。在美国,包括不健康生活方式的联合组织，慢性疾病,和COVID-19导致不必要的住院和死亡。大流行的政治化，社会经济不平等和区域文化价值观有意义地导致了这种联合期间不良结果的分布不均。共病的组成部分是可以避免的，不应重复。摘要：不健康的生活方式——慢性疾病——COVID-19美国综合征导致不必要的住院和死亡。大流行的政治化，社会经济不平等和区域文化价值观有意义地导致了这种联合期间不良结果的分布不均。共病的组成部分是可以避免的，不应重复。
