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Abstract：
BACKGROUND: A subpopulation of adults who smoke cigarettes use electronic nicotine device systems (ENDS) for cigarette cessation. This study examined the relationship between ENDS flavors, device types, and nicotine concentration with past month cigarette abstinence among adults using ENDS for cigarette cessation.
METHODS: We used the Population Assessment of Tobacco and Health (PATH) Study (waves 5 and 6) to identify adults who self-reported using ENDS to quit cigarettes at baseline (wave 5) and investigated their cigarette abstinence at follow-up (wave 6) [n = 1252]. Measures assessed include ENDS features (flavors, device types, nicotine concentration) at baseline and past-month abstinence from cigarette smoking at follow-up. Weighted descriptive analysis was used, and multivariable logistic regression models examined ENDS features associated with past-month cigarette abstinence, adjusting for demographic factors and tobacco dependence at baseline.
RESULTS: Most participants used disposable devices (37.2 %; 95 % CI:33.2-41.5), followed by refillable tanks (30.2 %; 95 % CI:26.2-34.5). Additionally, fruit (41.3 %; 95 % CI:37.3-45.5), followed by menthol (19.1 %; 95 % CI:16.2-22.4), and tobacco (18.5 %; 95 % CI:15.5-22.1) were the most common flavors. The most common nicotine concentration used was 1-6 mg/ml (38.8 %; 95 % CI:34.6-43.2). Furthermore, in the adjusted model, daily ENDS users at baseline had 86 % (95 % CI:1.08-3.18) higher odds of past month cigarette abstinence at follow-up, than individuals who indicated \'not at all\' to the current use of ENDS at baseline. There were no significant differences by preferred flavors, device type and nicotine concentrations (p-values > 0.05).
CONCLUSIONS: Daily ENDS users had higher odds of quitting cigarettes compared to those who stopped using ENDS. However, the type of device, flavoring, and nicotine concentration used by ENDS users were not associated with past-month cigarette abstinence at follow-up two years later.
METHODS: We used the Population Assessment of Tobacco and Health (PATH) Study (waves 5 and 6) to identify adults who self-reported using ENDS to quit cigarettes at baseline (wave 5) and investigated their cigarette abstinence at follow-up (wave 6) [n = 1252]. Measures assessed include ENDS features (flavors, device types, nicotine concentration) at baseline and past-month abstinence from cigarette smoking at follow-up. Weighted descriptive analysis was used, and multivariable logistic regression models examined ENDS features associated with past-month cigarette abstinence, adjusting for demographic factors and tobacco dependence at baseline.
RESULTS: Most participants used disposable devices (37.2 %; 95 % CI:33.2-41.5), followed by refillable tanks (30.2 %; 95 % CI:26.2-34.5). Additionally, fruit (41.3 %; 95 % CI:37.3-45.5), followed by menthol (19.1 %; 95 % CI:16.2-22.4), and tobacco (18.5 %; 95 % CI:15.5-22.1) were the most common flavors. The most common nicotine concentration used was 1-6 mg/ml (38.8 %; 95 % CI:34.6-43.2). Furthermore, in the adjusted model, daily ENDS users at baseline had 86 % (95 % CI:1.08-3.18) higher odds of past month cigarette abstinence at follow-up, than individuals who indicated \'not at all\' to the current use of ENDS at baseline. There were no significant differences by preferred flavors, device type and nicotine concentrations (p-values > 0.05).
CONCLUSIONS: Daily ENDS users had higher odds of quitting cigarettes compared to those who stopped using ENDS. However, the type of device, flavoring, and nicotine concentration used by ENDS users were not associated with past-month cigarette abstinence at follow-up two years later.
摘要：
背景：吸烟的成年人亚群使用电子尼古丁装置系统（ENDS）戒烟。这项研究检查了ENDS风味之间的关系，设备类型,以及使用ENDS戒烟的成年人中尼古丁浓度与过去一个月的戒烟情况。
方法：我们使用烟草与健康人群评估（PATH）研究（第5波和第6波）来识别那些自我报告使用ENDS在基线时戒烟的成年人（第5波），并在随访时调查他们的戒烟情况（第6波）[n=1252]。评估的措施包括ENDS功能(口味，设备类型,尼古丁浓度）在基线和过去一个月的戒烟随访。采用加权描述性分析，和多变量逻辑回归模型检查了与过去一个月戒烟相关的ENDS特征，调整基线时的人口统计学因素和烟草依赖。
结果：大多数参与者使用一次性设备（37.2％；95％CI：33.2-41.5），其次是可再填充罐（30.2%；95%CI：26.2-34.5）。此外,水果（41.3%；95%CI：37.3-45.5），其次是薄荷醇（19.1%；95%CI：16.2-22.4），和烟草(18.5%;95%CI:15.5-22.1)是最常见的口味。使用的最常见的尼古丁浓度为1-6mg/ml（38.8％；95％CI：34.6-43.2）。此外，在调整后的模型中，基线时的每日ENDS使用者在随访时上个月戒烟的几率较高，为86％（95％CI：1.08-3.18），比在基线时对当前使用ENDS表示“根本没有”的个人。不同口味的偏好没有显著差异，设备类型和尼古丁浓度（p值>0.05）。
结论：与停止使用ENDS的人相比，每日ENDS使用者戒烟的几率更高。然而,设备的类型，调味,在两年后的随访中,ENDS使用者使用的尼古丁浓度与过去一个月的戒烟无关.
方法：我们使用烟草与健康人群评估（PATH）研究（第5波和第6波）来识别那些自我报告使用ENDS在基线时戒烟的成年人（第5波），并在随访时调查他们的戒烟情况（第6波）[n=1252]。评估的措施包括ENDS功能(口味，设备类型,尼古丁浓度）在基线和过去一个月的戒烟随访。采用加权描述性分析，和多变量逻辑回归模型检查了与过去一个月戒烟相关的ENDS特征，调整基线时的人口统计学因素和烟草依赖。
结果：大多数参与者使用一次性设备（37.2％；95％CI：33.2-41.5），其次是可再填充罐（30.2%；95%CI：26.2-34.5）。此外,水果（41.3%；95%CI：37.3-45.5），其次是薄荷醇（19.1%；95%CI：16.2-22.4），和烟草(18.5%;95%CI:15.5-22.1)是最常见的口味。使用的最常见的尼古丁浓度为1-6mg/ml（38.8％；95％CI：34.6-43.2）。此外，在调整后的模型中，基线时的每日ENDS使用者在随访时上个月戒烟的几率较高，为86％（95％CI：1.08-3.18），比在基线时对当前使用ENDS表示“根本没有”的个人。不同口味的偏好没有显著差异，设备类型和尼古丁浓度（p值>0.05）。
结论：与停止使用ENDS的人相比，每日ENDS使用者戒烟的几率更高。然而,设备的类型，调味,在两年后的随访中,ENDS使用者使用的尼古丁浓度与过去一个月的戒烟无关.
