PDF(Pubmed)
Abstract：
Movement-related cortical potential (MRCP) is observed in EEG recordings prior to a voluntary movement. It has been used for e.g., quantifying motor learning and for brain-computer interfacing (BCIs). The MRCP amplitude is affected by various factors, but the effect of caffeine is underexplored. The aim of this study was to investigate if a cup of coffee with 85 mg caffeine modulated the MRCP amplitude and the classification of MRCPs versus idle activity, which estimates BCI performance. Twenty-six healthy participants performed 2 × 100 ankle dorsiflexion separated by a 10-min break before a cup of coffee was consumed, followed by another 100 movements. EEG was recorded during the movements and divided into epochs, which were averaged to extract three average MRCPs that were compared. Also, idle activity epochs were extracted. Features were extracted from the epochs and classified using random forest analysis. The MRCP amplitude did not change after consuming caffeine. There was a slight increase of two percentage points in the classification accuracy after consuming caffeine. In conclusion, a cup of coffee with 85 mg caffeine does not affect the MRCP amplitude, and improves MRCP-based BCI performance slightly. The findings suggest that drinking coffee is only a minor confounder in MRCP-related studies.
摘要：
在自愿运动之前的EEG记录中观察到运动相关的皮质电位（MRCP）。它已用于例如，量化运动学习和脑机接口(BCI)。MRCP振幅受各种因素的影响，但是咖啡因的效果没有得到充分的开发。这项研究的目的是研究一杯含有85毫克咖啡因的咖啡是否能调节MRCP的幅度和MRCP与空闲活动的分类，它估计BCI的表现。26名健康参与者进行了2×100的踝关节背屈，休息10分钟，然后喝杯咖啡，接下来是另外100个动作。在运动过程中记录EEG，并分为多个时期，将其平均提取三个比较的平均MRCP。此外，提取了空闲活动时期。从时代提取特征并使用随机森林分析进行分类。摄入咖啡因后，MRCP振幅没有变化。摄入咖啡因后，分类准确性略有提高两个百分点。总之,一杯含有85毫克咖啡因的咖啡不会影响MRCP的振幅，并略微提高了基于MRCP的BCI性能。研究结果表明，在MRCP相关研究中，喝咖啡只是一个次要的混淆因素。
