关键词: Warshaw procedure pediatric case solid pseudopapillary neoplasm

Mesh : Humans Laparoscopy / methods Pancreatic Neoplasms / surgery pathology Child Female Feasibility Studies Pancreatectomy / methods Male Treatment Outcome Adolescent Carcinoma, Papillary / surgery pathology Operative Time

来  源:   DOI:10.1111/ases.13336

Abstract:
Achieving margin-negative resection is crucial in treatment of solid pseudopapillary neoplasm (SPN) of the pancreas, while preserving the spleen during distal pancreatectomy is highly desirable in pediatric cases. Laparoscopic Warshaw procedure (Lap-WT) is invaluable when tumor involvement in splenic vessels complicates preservation. However, the feasibility of Lap-WT in pediatric patients remains contentious. This study presents the clinical outcomes of three pediatric SPN cases who underwent Lap-WT. The median age was 10 years, with a median tumor size of 50 mm. Lap-WT demonstrated successful outcomes with a median operation time of 311 min and blood loss of 12 mL. No postoperative complications occurred, with a median length of hospital stay of 8 days. Long-term follow-up showed mild thrombocytopenia and increased spleen volume in two cases, perigastric varices in one, with no bleeding complications. No instances of tumor recurrence were observed. Lap-WT emerges as a feasible approach for pediatric SPN, ensuring spleen preservation without compromising oncological outcomes.
摘要:
获得切缘阴性切除对胰腺实性假乳头状瘤(SPN)的治疗至关重要,在儿科病例中,在远端胰腺切除术期间保留脾脏是非常理想的。当肿瘤累及脾血管使保存复杂化时,腹腔镜Warshaw手术(Lap-WT)是无价的。然而,Lap-WT在儿科患者中的可行性仍存在争议。这项研究介绍了三例接受Lap-WT的小儿SPN病例的临床结果。中位年龄为10岁,中位肿瘤大小为50毫米。Lap-WT显示出成功的结果,中位手术时间为311分钟,失血量为12mL。术后无并发症发生,平均住院时间为8天。长期随访显示2例轻度血小板减少,脾脏体积增大,胃周静脉曲张合二为一,无出血并发症。没有观察到肿瘤复发的实例。Lap-WT成为儿科SPN的可行方法,确保保存脾脏而不损害肿瘤预后。
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