Abstract：
Leveraging electrochemistry, a new synthesis of non-natural derivatives of itaconic acid is proposed by utilizing carbon dioxide (CO2) as a valuable C1 synthon. An electrochemical cross-electrophile coupling between allenoates and CO2 was targeted, allowing for the synthesis of both mono- and di-carboxylation products in a catalyst- and additive-free environment (yields up to 87 %, 30 examples). Elaboration of the model mono-carboxylation product, and detailed cyclovoltammetric, as well as mechanistic analyses complete the present investigation.
摘要：
利用电化学，通过利用二氧化碳（CO2）作为有价值的C1合成子，提出了一种新的衣康酸非天然衍生物的合成方法。针对烯化酸盐和CO2之间的电化学交叉亲电耦合，允许在无催化剂和添加剂的环境中合成单羧化和双羧化产物(产率高达87%，30个例子)。模型单羧化产物的阐述，和详细的循环伏安法，以及机械分析完成了目前的调查。
