PDF(Pubmed)
Abstract：
The mosquito Aedes aegypti is distributed worldwide and is recognized as the primary vector for dengue in numerous countries. To investigate whether the fitness cost of a single DENV-1 isolate varies among populations, we selected four Ae. aegypti populations from distinct localities: Australia (AUS), Brazil (BRA), Pakistan (PAK), and Peru (PER). Utilizing simple methodologies, we concurrently assessed survival rates and fecundity. Overall, DENV-1 infection led to a significant decrease in mosquito survival rates, with the exception of the PER population. Furthermore, infected Ae. aegypti from PAK, the population with the lowest infection rate among those tested, exhibited a noteworthy reduction in egg laying. These findings collectively suggest that local mosquito-virus adaptations may influence dengue transmission in endemic settings.
摘要：
埃及伊蚊分布在世界各地，在许多国家被认为是登革热的主要媒介。为了调查单个DENV-1分离株的健身成本是否因人群而异，我们选择了四个Ae。来自不同地区的埃及伊蚊种群：澳大利亚（AUS），巴西(BRA),巴基斯坦(PAK),秘鲁（PER）。利用简单的方法，我们同时评估了生存率和繁殖力.总的来说,DENV-1感染导致蚊子存活率显著下降，除了每个人口。此外，感染Ae.来自PAK的埃及伊蚊，受检测人群中感染率最低的人群，产卵显着减少。这些发现共同表明，当地的蚊子病毒适应可能会影响流行环境中的登革热传播。
