{Reference Type}: Journal Article
{Title}: Dengue Virus Serotype 1 Effects on Mosquito Survival Differ among Geographically Distinct Aedes aegypti Populations.
{Author}: Keirsebelik MSG;David MR;Pavan MG;Couto-Lima D;Palomino M;Rahman RU;Hoffmann AA;Bahia AC;Caljon G;Maciel-de-Freitas R;
{Journal}: Insects
{Volume}: 15
{Issue}: 6
{Year}: 2024 May 28
{Factor}: 3.139
{DOI}: 10.3390/insects15060393
{Abstract}: The mosquito Aedes aegypti is distributed worldwide and is recognized as the primary vector for dengue in numerous countries. To investigate whether the fitness cost of a single DENV-1 isolate varies among populations, we selected four Ae. aegypti populations from distinct localities: Australia (AUS), Brazil (BRA), Pakistan (PAK), and Peru (PER). Utilizing simple methodologies, we concurrently assessed survival rates and fecundity. Overall, DENV-1 infection led to a significant decrease in mosquito survival rates, with the exception of the PER population. Furthermore, infected Ae. aegypti from PAK, the population with the lowest infection rate among those tested, exhibited a noteworthy reduction in egg laying. These findings collectively suggest that local mosquito-virus adaptations may influence dengue transmission in endemic settings.