%0 Journal Article
%T Dengue Virus Serotype 1 Effects on Mosquito Survival Differ among Geographically Distinct Aedes aegypti Populations.
%A Keirsebelik MSG
%A David MR
%A Pavan MG
%A Couto-Lima D
%A Palomino M
%A Rahman RU
%A Hoffmann AA
%A Bahia AC
%A Caljon G
%A Maciel-de-Freitas R
%J Insects
%V 15
%N 6
%D 2024 May 28
%M 38921108
%F 3.139
%R 10.3390/insects15060393
%X The mosquito Aedes aegypti is distributed worldwide and is recognized as the primary vector for dengue in numerous countries. To investigate whether the fitness cost of a single DENV-1 isolate varies among populations, we selected four Ae. aegypti populations from distinct localities: Australia (AUS), Brazil (BRA), Pakistan (PAK), and Peru (PER). Utilizing simple methodologies, we concurrently assessed survival rates and fecundity. Overall, DENV-1 infection led to a significant decrease in mosquito survival rates, with the exception of the PER population. Furthermore, infected Ae. aegypti from PAK, the population with the lowest infection rate among those tested, exhibited a noteworthy reduction in egg laying. These findings collectively suggest that local mosquito-virus adaptations may influence dengue transmission in endemic settings.