关键词: assisted reproductive technology atypical endometrial hyperplasia endometrial cancer fertility-sparing treatment pregnancy outcome

Mesh : Humans Female Endometrial Neoplasms / therapy pathology Reproductive Techniques, Assisted Endometrial Hyperplasia / therapy pathology Pregnancy Conservative Treatment / methods Fertility Preservation / methods Pregnancy Outcome Infertility, Female / therapy etiology

来  源:   DOI:10.3389/fendo.2024.1377396   PDF(Pubmed)

Abstract:
As the incidence of endometrial cancer (EC) and atypical endometrial hyperplasia (AEH) has been increasing, and has shown young trend. It is crucial to study the fertility-preserving treatment of endometrial lesions and fertility-promoting protocols. Age, obesity, and irregular ovulation are not only high-risk factors for endometrial lesions but also key factors affecting female fertility. Assisted reproductive technology (ART) can significantly improve pregnancy outcomes in patients with AEH and EC after conservative treatment. Based on the existing studies, this article reviews the progress of research on pregnancy outcomes of ART and its influencing factors in such patients. It helps physicians in providing optimal fertility guidance.
摘要:
随着子宫内膜癌(EC)和不典型子宫内膜增生(AEH)的发病率不断增加,并显示出年轻的趋势。研究子宫内膜病变的保留生育治疗和促进生育的方案至关重要。年龄,肥胖,不规则排卵不仅是子宫内膜病变的高危因素,也是影响女性生育的关键因素。辅助生殖技术(ART)可显著改善AEH合并EC患者保守治疗后的妊娠结局。在现有研究的基础上,本文就ART对此类患者妊娠结局及其影响因素的研究进展作一综述。它可以帮助医生提供最佳的生育指导。
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