Abstract：
BACKGROUND: An athlete\'s career inevitably goes through periods of forced physical exercise interruption like a knee injury. Advanced echocardiographic methods and cardiopulmonary exercise testing (CPET) are essential in evaluating athletes in the period elapsing after the injury. However, the feasibility of a maximal pre-surgery CPET and the capacity of resting advanced echocardiographic techniques to predict cardiorespiratory capacity still need to be clarified.
METHODS: We evaluated 28 non-professional athletes aged 18-52, involved in prevalently aerobic or alternate aerobic/anaerobic sports activities, affected by a knee pathology with indications for surgical treatment. The evaluation was performed at rest by trans-thoracic echocardiography, including global longitudinal strain (GLS) and myocardial work (MW) assessment, and during exercise by CPET.
RESULTS: The percent-predicted peak oxygen consumption (peak VO2 %) was 82.8±13.7%, the mean respiratory exchange ratio was 1.16±0.08, and the mean ventilation/carbon dioxide (VE /VCO2 ) slope was 24.23±3.36. Peak VO2 % negatively correlated with GLS (r=-0.518, P=0.003) and global wasted work (GWW) (r =-0.441, P=0.015) and positively correlated with global work efficiency (GWE) (r=0.455, P=0.012). Finally, we found that the VE /VCO2 slope during exercise was negatively correlated with GWE (r=-0.585, P=0.001) and positively correlated with GWW (r=0.499, P=0.005).
CONCLUSIONS: A maximal CPET can be obtained in deconditioned athletes because of a knee injury, allowing a comprehensive functional pre-surgery evaluation. In these patients, peak VO2 is reduced due to decreased physical activity after injury; however, a lower cardiopulmonary efficiency may be a concause of the injury itself. In addition, we demonstrated that the MW indexes obtained at rest could predict exercise capacity and ventilatory efficiency as evaluated by CPET.
METHODS: We evaluated 28 non-professional athletes aged 18-52, involved in prevalently aerobic or alternate aerobic/anaerobic sports activities, affected by a knee pathology with indications for surgical treatment. The evaluation was performed at rest by trans-thoracic echocardiography, including global longitudinal strain (GLS) and myocardial work (MW) assessment, and during exercise by CPET.
RESULTS: The percent-predicted peak oxygen consumption (peak VO
CONCLUSIONS: A maximal CPET can be obtained in deconditioned athletes because of a knee injury, allowing a comprehensive functional pre-surgery evaluation. In these patients, peak VO
摘要：
背景：运动员的职业生涯不可避免地要经历像膝盖受伤一样的强迫体育锻炼中断时期。先进的超声心动图方法和心肺运动测试（CPET）对于评估受伤后一段时间的运动员至关重要。然而,最大术前CPET的可行性和静息高级超声心动图技术预测心肺容量的能力仍有待阐明.
方法：我们评估了28名年龄在18-52岁之间的非职业运动员，他们普遍参与有氧或交替的有氧/无氧体育活动，受膝关节病理学影响，有手术治疗指征。通过经胸超声心动图在休息时进行评估，包括全球纵向应变(GLS)和心肌功(MW)评估，以及在CPET锻炼期间。
结果：预测的峰值耗氧量百分比（峰值VO2 ％）为82.8±13.7％，平均呼吸交换比为1.16±0.08，平均通气/二氧化碳（VE /VCO2 ）斜率为24.23±3.36。峰值VO2 %与GLS(r=-0.518,P=0.003)和全局浪费工作(GWW)(r=-0.441,P=0.015)呈负相关,与全局工作效率(GWE)呈正相关(r=0.455,P=0.012)。最后,我们发现运动过程中VE /VCO2 斜率与GWE呈负相关（r=-0.585，P=0.001），与GWW呈正相关（r=0.499，P=0.005）。
结论：由于膝盖受伤，取消训练的运动员可以获得最大的CPET，允许全面的手术前功能评估。在这些患者中,由于受伤后体力活动减少，峰值VO2 降低；然而，心肺效率降低可能是损伤本身的原因。此外,我们证明，静息时获得的MW指数可以预测CPET评估的运动能力和通气效率。
方法：我们评估了28名年龄在18-52岁之间的非职业运动员，他们普遍参与有氧或交替的有氧/无氧体育活动，受膝关节病理学影响，有手术治疗指征。通过经胸超声心动图在休息时进行评估，包括全球纵向应变(GLS)和心肌功(MW)评估，以及在CPET锻炼期间。
结果：预测的峰值耗氧量百分比（峰值VO
结论：由于膝盖受伤，取消训练的运动员可以获得最大的CPET，允许全面的手术前功能评估。在这些患者中,由于受伤后体力活动减少，峰值VO
