Abstract：
The increase of multiple drug resistance bacteria significantly diminishes the effectiveness of antibiotic armory and subsequently exaggerates the level of therapeutic failure. Phytoconstituents are exceptional substitutes for resistance-modifying vehicles. The plants appear to be a deep well for the discovery of novel antibacterial compounds. This is owing to the numerous enticing characteristics of plants, they are easily accessible and inexpensive, extracts or chemicals derived from plants typically have significant levels of action against infections, and they rarely cause serious adverse effects. The enormous selection of phytochemicals offers very distinct chemical structures that may provide both novel mechanisms of antimicrobial activity and deliver us with different targets in the interior of the bacterial cell. They can directly affect bacteria or act together with the crucial events of pathogenicity, in this manner decreasing the aptitude of bacteria to create resistance. Abundant phytoconstituents demonstrate various mechanisms of action toward multi drug resistance bacteria. Overall, this comprehensive review will provide insights into the potential of phytoconstituents as alternative treatments for bacterial infections, particularly those caused by multi drug resistance strains. By examining the current state of research in this area, the review will shed light on potential future directions for the development of new antimicrobial therapies.
摘要：
多重耐药性细菌的增加显着降低了抗生素药库的有效性，并随后夸大了治疗失败的程度。植物成分是抗性改性车辆的特殊替代品。这些植物似乎是发现新型抗菌化合物的深井。这是由于植物的许多诱人的特性，它们很容易获得且便宜，来自植物的提取物或化学物质通常具有显著的抗感染作用，它们很少引起严重的不良影响。植物化学物质的大量选择提供了非常独特的化学结构，可以提供抗菌活性的新机制，并在细菌细胞内部为我们提供不同的靶标。它们可以直接影响细菌或与致病性的关键事件一起起作用，以这种方式降低细菌产生抗性的能力。丰富的植物成分证明了对多药耐药细菌的各种作用机制。总的来说,这篇全面的综述将提供有关植物成分作为细菌感染替代疗法的潜力的见解，特别是由多药耐药菌株引起的。通过考察这一领域的研究现状，该综述将阐明开发新的抗微生物疗法的潜在未来方向。
