PDF(Pubmed)
Abstract：
Several pharmacological effects were described for Nigella sativa (N. sativa) seed and it has been used traditionally to treat various diseases. In this review article, the updated and comprehensive anti-oxidant effects of N. sativa and its main constituent, thymoquinone (TQ), on various disorders are described. The relevant articles were retrieved through PubMed, Science Direct, and Scopus up to December 31, 2023. Various extracts and essential oils of N. sativa showed anti-oxidant effects on cardiovascular, endocrine, gastrointestinal and liver, neurologic, respiratory, and urogenital diseases by decreasing and increasing various oxidant and anti-oxidant marketers, respectively. The main constituent of the plant, TQ, also showed similar anti-oxidant effects as the plant itself. The anti-oxidant effects of different extracts and essential oils of N. sativa were demonstrated in various studies which were perhaps due to the main constituent of the plant, TQ. The findings of this review article suggest the possible therapeutic effect of N. sativa and TQ in oxidative stress disorders.
摘要：
对Nigellasativa（N.紫花苜蓿）种子，传统上已用于治疗各种疾病。在这篇评论文章中，紫花苜蓿及其主要成分的最新和全面的抗氧化作用，百里香醌(TQ),对各种疾病进行了描述。相关文章是通过PubMed检索的，科学直接，和Scopus至2023年12月31日。紫花苜蓿的各种提取物和精油对心血管有抗氧化作用，内分泌，胃肠和肝脏，神经学，呼吸,通过减少和增加各种氧化剂和抗氧化剂营销商，分别。植物的主要成分，TQ,还显示出与植物本身相似的抗氧化作用。在各种研究中证明了不同提取物和紫花苜蓿精油的抗氧化作用，这可能是由于植物的主要成分。TQ.这篇综述文章的研究结果表明，紫花苜蓿和TQ在氧化应激障碍中可能的治疗作用。
