Abstract：
To summarize studies published between 2017 and 2023 examining the clinical diagnosis and restorative management of amelogenesis imperfecta (AI) in children and adolescents.
The review incorporated publications on clinical diagnosis, patient-reported outcomes, clinical trials, cohort studies, and case reports that included individuals below 19 years of age with non-syndromic AI.
A literature search was conducted across electronic databases, PubMed, Web of Science, and CINAHL, including papers published between 2017 and 2023. The search yielded 335 unique results, of which 38 were eligible for inclusion.
New evidence on the genetic background of AI makes it now advisable to recommend genetic testing to supplement a clinical AI diagnosis. The discussions of the dental profession and the public on social media do not always incorporate recent scientific evidence. Interview studies are finding that the impact of AI on quality of life is more severe than previously appreciated. New evidence suggests that single-tooth ceramic crowns should be the first choice of treatment. Due to incomplete reporting, case reports have been of limited value.
In young patients with AI symptoms of pain and hypersensitivity decreased, and aesthetics were improved following all types of restorative therapy. Resin composite restorations were mainly performed in cases with hypoplastic AI and mild symptoms. Single tooth ceramic crown restorations have a high success rate in all types of AI and can be used in young individuals with AI.
Prosthetic rehabilitation in adolescents with severe AI is cost effective, improves esthetics, reduces tooth sensitivity, and improves oral health-related quality of life.
The review incorporated publications on clinical diagnosis, patient-reported outcomes, clinical trials, cohort studies, and case reports that included individuals below 19 years of age with non-syndromic AI.
A literature search was conducted across electronic databases, PubMed, Web of Science, and CINAHL, including papers published between 2017 and 2023. The search yielded 335 unique results, of which 38 were eligible for inclusion.
New evidence on the genetic background of AI makes it now advisable to recommend genetic testing to supplement a clinical AI diagnosis. The discussions of the dental profession and the public on social media do not always incorporate recent scientific evidence. Interview studies are finding that the impact of AI on quality of life is more severe than previously appreciated. New evidence suggests that single-tooth ceramic crowns should be the first choice of treatment. Due to incomplete reporting, case reports have been of limited value.
In young patients with AI symptoms of pain and hypersensitivity decreased, and aesthetics were improved following all types of restorative therapy. Resin composite restorations were mainly performed in cases with hypoplastic AI and mild symptoms. Single tooth ceramic crown restorations have a high success rate in all types of AI and can be used in young individuals with AI.
Prosthetic rehabilitation in adolescents with severe AI is cost effective, improves esthetics, reduces tooth sensitivity, and improves oral health-related quality of life.
摘要：
目的：总结2017年至2023年发表的研究，探讨儿童和青少年牙釉质发育不全（AI）的临床诊断和修复管理。
方法：该综述纳入了有关临床诊断，患者报告的结果，临床试验,队列研究，和病例报告，其中包括19岁以下的非综合征性AI个体。
方法：在电子数据库中进行了文献检索，PubMed,WebofScience,和CINAHL，包括2017-2023年间发表的论文。搜索产生了335个独特的结果，其中38人符合入选条件。
结果：关于AI遗传背景的新证据使得现在建议推荐基因检测来补充临床AI诊断。牙科专业和公众在社交媒体上的讨论并不总是包含最近的科学证据。访谈研究发现，人工智能对生活质量的影响比以前认识到的更严重。新证据表明，单齿陶瓷牙冠应该是首选治疗方法。由于报告不完整，病例报告价值有限。
结论：在年轻的AI患者中，疼痛和超敏反应症状减轻，在所有类型的恢复性治疗后，美学都得到了改善。树脂复合修复主要在AI发育不良和轻度症状的情况下进行。单齿陶瓷冠修复在所有类型的AI中都具有很高的成功率，并且可以用于患有AI的年轻人。
结论：重度AI青少年的假肢康复具有成本效益，提高美学，降低牙齿敏感度，改善与口腔健康相关的生活质量。
方法：该综述纳入了有关临床诊断，患者报告的结果，临床试验,队列研究，和病例报告，其中包括19岁以下的非综合征性AI个体。
方法：在电子数据库中进行了文献检索，PubMed,WebofScience,和CINAHL，包括2017-2023年间发表的论文。搜索产生了335个独特的结果，其中38人符合入选条件。
结果：关于AI遗传背景的新证据使得现在建议推荐基因检测来补充临床AI诊断。牙科专业和公众在社交媒体上的讨论并不总是包含最近的科学证据。访谈研究发现，人工智能对生活质量的影响比以前认识到的更严重。新证据表明，单齿陶瓷牙冠应该是首选治疗方法。由于报告不完整，病例报告价值有限。
结论：在年轻的AI患者中，疼痛和超敏反应症状减轻，在所有类型的恢复性治疗后，美学都得到了改善。树脂复合修复主要在AI发育不良和轻度症状的情况下进行。单齿陶瓷冠修复在所有类型的AI中都具有很高的成功率，并且可以用于患有AI的年轻人。
结论：重度AI青少年的假肢康复具有成本效益，提高美学，降低牙齿敏感度，改善与口腔健康相关的生活质量。
