Abstract：
This chapter aims to explore the usefulness of the latest advances in genetic studies in the field of the circadian system in the future development of individualised strategies for health improvement based on lifestyle intervention. Due to the multifactorial and complex nature of the circadian system, we focus on the highly prevalent phenotypes in the population that are key to understanding its biology from an evolutionary perspective and that can be modulated by lifestyle. Therefore, we leave in the background those phenotypes that constitute infrequent pathologies or in which the current level of scientific evidence does not favour the implementation of practical approaches of this type. Therefore, from an evolutionary paradigm, this chapter addresses phenotypes such as morning chronotypes, evening chronotypes, extreme chronotypes, and other key concepts such as circadian rhythm amplitude, resilience to changes in circadian rhythm, and their relationships with pathologies associated with circadian rhythm imbalances.
摘要：
本章旨在探讨基因研究在昼夜节律系统领域的最新进展在未来发展基于生活方式干预的个性化健康改善策略中的有用性。由于昼夜节律系统的多因素和复杂性，我们关注人群中非常普遍的表型，这些表型对于从进化的角度理解其生物学至关重要，并且可以通过生活方式进行调节。因此,我们将那些构成罕见病理或当前科学证据水平不支持实施此类实用方法的表型留在背景中.因此,从进化范式中，本章介绍了表型，如早晨时间型，晚上的时间类型，极端的时间型，和其他关键概念，如昼夜节律振幅，适应昼夜节律变化，以及它们与昼夜节律失衡相关病理的关系。
