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Abstract：
BACKGROUND: In this study we investigated the impact of ABC stroke score on the recurrence of paroxysmal atrial fibrillation (PAF) following radiofrequency catheter ablation (RFCA).
METHODS: A total of 132 patients with PAF who underwent RFCA from October 2018 to September 2019 were included in this study. During the first phase of this study the patients were categorized into two groups based on late recurrence of atrial fibrillation after RFCA. In the second phase, the patients were further divided into two groups based on whether their ABC stroke score was ≥ 6.5.
RESULTS: The univariate analysis indicated that the risk factors for late recurrence of PAF included early recurrence, ABC stroke score, CHA2DS2-VASc score, and NT-proBNP (P < 0.05). Cox multivariate regression analysis revealed that ABC stroke score (P = 0.006) and early recurrence (P = 0.000) were independent predictors of late recurrence, and ABC stroke score ≥ 6.5 was a risk for predicting recurrence of PAF after RFCA with a sensitivity of 66.7% and specificity of 65.7%. After the completion of the 1:1 matching, the univariate Cox analysis indicated that an elevated score of ABC stroke (≥ 6.5) was an independent predictor of late recurrence of PAF (HR = 2.687, 95% CI: 1.036-6.971, P = 0.042). However, using an ABC stroke score cut off at 6.4 predicted the recurrence of atrial tachyarrhythmia with 85% sensitivity and 58.5% specificity.
CONCLUSIONS: An ABC stroke score ≥ 6.4 is a predictor for late recurrence of PAF after RFCA.
METHODS: A total of 132 patients with PAF who underwent RFCA from October 2018 to September 2019 were included in this study. During the first phase of this study the patients were categorized into two groups based on late recurrence of atrial fibrillation after RFCA. In the second phase, the patients were further divided into two groups based on whether their ABC stroke score was ≥ 6.5.
RESULTS: The univariate analysis indicated that the risk factors for late recurrence of PAF included early recurrence, ABC stroke score, CHA2DS2-VASc score, and NT-proBNP (P < 0.05). Cox multivariate regression analysis revealed that ABC stroke score (P = 0.006) and early recurrence (P = 0.000) were independent predictors of late recurrence, and ABC stroke score ≥ 6.5 was a risk for predicting recurrence of PAF after RFCA with a sensitivity of 66.7% and specificity of 65.7%. After the completion of the 1:1 matching, the univariate Cox analysis indicated that an elevated score of ABC stroke (≥ 6.5) was an independent predictor of late recurrence of PAF (HR = 2.687, 95% CI: 1.036-6.971, P = 0.042). However, using an ABC stroke score cut off at 6.4 predicted the recurrence of atrial tachyarrhythmia with 85% sensitivity and 58.5% specificity.
CONCLUSIONS: An ABC stroke score ≥ 6.4 is a predictor for late recurrence of PAF after RFCA.
摘要：
背景：在这项研究中，我们调查了ABC卒中评分对射频导管消融（RFCA）后阵发性心房颤动（PAF）复发的影响。
方法：本研究纳入了2018年10月至2019年9月接受RFCA的132例PAF患者。在本研究的第一阶段，根据RFCA后房颤的晚期复发将患者分为两组。在第二阶段,根据ABC卒中评分是否≥6.5,将患者进一步分为两组.
结果：单因素分析表明PAF晚期复发的危险因素包括早期复发，ABC中风评分,CHA2DS2-VASc评分,NT-proBNP(P<0.05)。Cox多因素回归分析显示,ABC卒中评分(P=0.006)和早期复发(P=0.000)是晚期复发的独立预测因子。ABC卒中评分≥6.5是预测RFCA后PAF复发的风险,其敏感性为66.7%,特异性为65.7%.1:1匹配完成后，单因素Cox分析显示,ABC卒中评分升高(≥6.5)是PAF晚期复发的独立预测因子(HR=2.687,95%CI:1.036~6.971,P=0.042).然而,在6.4时采用ABC卒中评分,预测房性快速性心律失常复发的敏感性为85%,特异性为58.5%.
结论：ABC卒中评分≥6.4是RFCA后PAF晚期复发的预测因子。
方法：本研究纳入了2018年10月至2019年9月接受RFCA的132例PAF患者。在本研究的第一阶段，根据RFCA后房颤的晚期复发将患者分为两组。在第二阶段,根据ABC卒中评分是否≥6.5,将患者进一步分为两组.
结果：单因素分析表明PAF晚期复发的危险因素包括早期复发，ABC中风评分,CHA2DS2-VASc评分,NT-proBNP(P<0.05)。Cox多因素回归分析显示,ABC卒中评分(P=0.006)和早期复发(P=0.000)是晚期复发的独立预测因子。ABC卒中评分≥6.5是预测RFCA后PAF复发的风险,其敏感性为66.7%,特异性为65.7%.1:1匹配完成后，单因素Cox分析显示,ABC卒中评分升高(≥6.5)是PAF晚期复发的独立预测因子(HR=2.687,95%CI:1.036~6.971,P=0.042).然而,在6.4时采用ABC卒中评分,预测房性快速性心律失常复发的敏感性为85%,特异性为58.5%.
结论：ABC卒中评分≥6.4是RFCA后PAF晚期复发的预测因子。
