Abstract：
UNASSIGNED: Exertional rhabdomyolysis (ER) is caused by myocyte breakdown after strenuous physical activity. In recent years, the incidence of spin-induced ER (SER) has been increasing. We describe the clinical characteristics, management and outcomes of patients admitted for SER.
UNASSIGNED: A review was conducted for all patients admitted to Singapore General Hospital for SER from 1 March 2021 to 31 March 2022. All patients with the admission diagnosis of \"rhabdomyolysis\", \"raised creatine kinase (CK) level\", or \"elevated CK level\" with a preceding history of spin-related physical exertion were included. Patients without a history of exertion, with a history of non-spin related exertion, or with a peak serum CK <1000 U/L were excluded.
UNASSIGNED: There were 93 patients in our final analysis; mean age was 28.6±5.6 years and 66 (71.0%) were female patients. Mean body mass index was 25.0±5.7 kg/m2; 81 (87.1%) patients were first-time spin participants. All patients had muscle pain, 68 (73.1%) had dark urine, 16 (17.2%) muscle swelling and 14 (15.1%) muscle weakness. There were 80 (86.0%) patients with admission CK of >20,000 U/L. Mean admission creatinine was 59.6±15.6 μmol/L. Mean intravenous (IV) hydration received was 2201±496 mL/ day, oral hydration 1217±634 mL/day and total hydration 3417±854 mL/day. There was 1 (1.1%) patient with acute kidney injury, which resolved the next day with IV hydration.
UNASSIGNED: Inpatient management of SER includes laboratory investigations, analgesia and hydration. Risk of complications is low in SER patients. SER patients without risk factors for complications can be considered for hospital-at-home management with bed rest, aggressive hydration and early outpatient review.
UNASSIGNED: A review was conducted for all patients admitted to Singapore General Hospital for SER from 1 March 2021 to 31 March 2022. All patients with the admission diagnosis of \"rhabdomyolysis\", \"raised creatine kinase (CK) level\", or \"elevated CK level\" with a preceding history of spin-related physical exertion were included. Patients without a history of exertion, with a history of non-spin related exertion, or with a peak serum CK <1000 U/L were excluded.
UNASSIGNED: There were 93 patients in our final analysis; mean age was 28.6±5.6 years and 66 (71.0%) were female patients. Mean body mass index was 25.0±5.7 kg/m2; 81 (87.1%) patients were first-time spin participants. All patients had muscle pain, 68 (73.1%) had dark urine, 16 (17.2%) muscle swelling and 14 (15.1%) muscle weakness. There were 80 (86.0%) patients with admission CK of >20,000 U/L. Mean admission creatinine was 59.6±15.6 μmol/L. Mean intravenous (IV) hydration received was 2201±496 mL/ day, oral hydration 1217±634 mL/day and total hydration 3417±854 mL/day. There was 1 (1.1%) patient with acute kidney injury, which resolved the next day with IV hydration.
UNASSIGNED: Inpatient management of SER includes laboratory investigations, analgesia and hydration. Risk of complications is low in SER patients. SER patients without risk factors for complications can be considered for hospital-at-home management with bed rest, aggressive hydration and early outpatient review.
摘要：
■劳力性横纹肌溶解症（ER）是由剧烈体力活动后的心肌细胞分解引起的。近年来,自旋诱导ER（SER）的发生率一直在增加。我们描述了临床特征，接受SER的患者的管理和结果。
对2021年3月1日至2022年3月31日新加坡总医院接受SER的所有患者进行了审查。所有入院诊断为“横纹肌溶解症”的患者，“肌酸激酶（CK）水平升高”，包括先前有与自旋相关的体力消耗史的“CK水平升高”。没有劳累史的病人，具有与旋转无关的运动历史，排除或峰值血清CK<1000U/L。
■在我们的最终分析中，有93例患者；平均年龄为28.6±5.6岁，66例（71.0％）为女性患者。平均体重指数为25.0±5.7kg/m2；81例（87.1％）患者为首次旋转参与者。所有患者都有肌肉疼痛,68（73.1%）有深色尿液，16（17.2%）肌肉肿胀和14（15.1%）肌肉无力。80例（86.0％）患者入院时CK>20,000U/L。平均入院肌酐为59.6±15.6μmol/L。接受的平均静脉（IV）水合作用为2201±496mL/天，口服水合1217±634mL/天，总水合3417±854mL/天。有1例（1.1%）急性肾损伤患者，第二天用静脉补水解决了。
■SER的住院管理包括实验室调查，镇痛和水合作用。SER患者发生并发症的风险较低。没有并发症危险因素的SER患者可以考虑在家中进行医院管理，卧床休息，积极的水化和早期门诊检查。
对2021年3月1日至2022年3月31日新加坡总医院接受SER的所有患者进行了审查。所有入院诊断为“横纹肌溶解症”的患者，“肌酸激酶（CK）水平升高”，包括先前有与自旋相关的体力消耗史的“CK水平升高”。没有劳累史的病人，具有与旋转无关的运动历史，排除或峰值血清CK<1000U/L。
■在我们的最终分析中，有93例患者；平均年龄为28.6±5.6岁，66例（71.0％）为女性患者。平均体重指数为25.0±5.7kg/m2；81例（87.1％）患者为首次旋转参与者。所有患者都有肌肉疼痛,68（73.1%）有深色尿液，16（17.2%）肌肉肿胀和14（15.1%）肌肉无力。80例（86.0％）患者入院时CK>20,000U/L。平均入院肌酐为59.6±15.6μmol/L。接受的平均静脉（IV）水合作用为2201±496mL/天，口服水合1217±634mL/天，总水合3417±854mL/天。有1例（1.1%）急性肾损伤患者，第二天用静脉补水解决了。
■SER的住院管理包括实验室调查，镇痛和水合作用。SER患者发生并发症的风险较低。没有并发症危险因素的SER患者可以考虑在家中进行医院管理，卧床休息，积极的水化和早期门诊检查。
