PDF(Pubmed)
Abstract：
OBJECTIVE: this study was to determine the relationship between acute febrile illness and bacterial pathogens with zoonotic potential that cause emerging and re-emerging diseases in a central-eastern region of Peru.
RESULTS: Out of the 279 samples analyzed, 23 (8.2%) tested positive for infection by Rickettsia spp., while a total of 15 (5.4%) tested positive for Leptospira spp. Women had a higher frequency of infection by Rickettsia spp., with 13 cases (53.3%), while men had a higher frequency of infection by Leptospira spp., with 10 cases (66.7%). The most frequently reported general symptom was headache, with 100.0% (n = 23) of patients with Rickettsia (+) and 86.7% (n = 13) of patients with Leptospira (+) experiencing it. Arthralgia was the second most frequent symptom, reported by 95.6% (n = 22) and 60% (n = 9) of patients with Rickettsia (+) and Leptospira (+), respectively. Myalgia was reported by 91.3% (n = 21) and 66.7% (n = 10) of patients with Rickettsia (+) and Leptospira (+), respectively. Retroocular pain, low back pain, and skin rash were also present, but less frequently. Among the positives, no manifestation of bleeding was recorded, although only one positive case for Leptospira spp. presented a decrease in the number of platelets.
RESULTS: Out of the 279 samples analyzed, 23 (8.2%) tested positive for infection by Rickettsia spp., while a total of 15 (5.4%) tested positive for Leptospira spp. Women had a higher frequency of infection by Rickettsia spp., with 13 cases (53.3%), while men had a higher frequency of infection by Leptospira spp., with 10 cases (66.7%). The most frequently reported general symptom was headache, with 100.0% (n = 23) of patients with Rickettsia (+) and 86.7% (n = 13) of patients with Leptospira (+) experiencing it. Arthralgia was the second most frequent symptom, reported by 95.6% (n = 22) and 60% (n = 9) of patients with Rickettsia (+) and Leptospira (+), respectively. Myalgia was reported by 91.3% (n = 21) and 66.7% (n = 10) of patients with Rickettsia (+) and Leptospira (+), respectively. Retroocular pain, low back pain, and skin rash were also present, but less frequently. Among the positives, no manifestation of bleeding was recorded, although only one positive case for Leptospira spp. presented a decrease in the number of platelets.
摘要：
目的：本研究旨在确定急性高热疾病与具有人畜共患潜力的细菌病原体之间的关系，这些病原体在秘鲁中东部地区引起新出现和重新出现的疾病。
结果：在分析的279个样本中，23（8.2％）的立克次体感染呈阳性。,而共有15人(5.4%)的钩端螺旋体属检测呈阳性。妇女感染立克次体的频率更高。,13例(53.3%)，而男性感染钩端螺旋体的频率更高。,10例(66.7%)。最常报告的一般症状是头痛，100.0％（n=23）的立克次体（）患者和86.7％（n=13）的钩端螺旋体（）患者经历了它。关节痛是第二常见的症状，报告了95.6%(n=22)和60%(n=9)的立克次体(+)和钩端螺旋体(+)患者，分别。有91.3%(n=21)和66.7%(n=10)的立克次体(+)和钩端螺旋体(+)患者报告肌痛,分别。眼后疼痛，腰痛,还出现了皮疹，但不太频繁。在积极的方面，没有出血的表现，尽管只有一例钩端螺旋体属阳性病例。呈现血小板数量的减少。
结果：在分析的279个样本中，23（8.2％）的立克次体感染呈阳性。,而共有15人(5.4%)的钩端螺旋体属检测呈阳性。妇女感染立克次体的频率更高。,13例(53.3%)，而男性感染钩端螺旋体的频率更高。,10例(66.7%)。最常报告的一般症状是头痛，100.0％（n=23）的立克次体（）患者和86.7％（n=13）的钩端螺旋体（）患者经历了它。关节痛是第二常见的症状，报告了95.6%(n=22)和60%(n=9)的立克次体(+)和钩端螺旋体(+)患者，分别。有91.3%(n=21)和66.7%(n=10)的立克次体(+)和钩端螺旋体(+)患者报告肌痛,分别。眼后疼痛，腰痛,还出现了皮疹，但不太频繁。在积极的方面，没有出血的表现，尽管只有一例钩端螺旋体属阳性病例。呈现血小板数量的减少。
