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Abstract：
BACKGROUND: Chronic cough has been associated with reduced health-related quality of life, negative impacts on sleep, work, and other daily activities, and increased use of health care resources. Little is known about the prevalence of chronic cough in Italy. In the present study we sought to estimate the prevalence of chronic cough in Italy, describe sociodemographic and clinical characteristics associated with chronic cough, and characterize the impact of chronic cough on overall health and wellness, work and other daily activities, and health care resource use.
METHODS: We conducted a cross-sectional study to collect sociodemographic and health-related data from Italian residents who participated in the 2020 National Health and Wellness Survey (N = 10,026). To assess the characteristics and burden of chronic cough, adults who indicated that they had experienced chronic cough during the prior 12 months were compared with propensity score-matched controls without chronic cough.
RESULTS: The estimated weighted lifetime and 12-month prevalence of chronic cough were estimated as 9.2% and 6.3%, respectively. Compared with matched controls, respondents with chronic cough had significantly lower measures of overall physical and mental health (P < .001 for both comparisons), and significantly higher rates of anxiety, depression, and sleep disorders (P < .001 for all comparisons). Chronic cough was significantly associated with higher rates of impairment of work and other activities (P < .001 for all comparisons) in the past 7 days, any-cause emergency department visits and hospitalizations in the prior 6 months (P < .001 for both comparisons), and more visits to general and specialist health care providers (P < .001 for both comparisons) in the prior 6 months.
CONCLUSIONS: In Italy, chronic cough affects an estimated 3.3 million adults annually and represents a significant burden to individuals and the health care system.
CONCLUSIONS: Little is known about the prevalence of chronic cough in Italy. We found that, in Italy chronic cough represents a significant burden to individuals and the health care system, affecting an estimated 3.3 million adults annually.
METHODS: We conducted a cross-sectional study to collect sociodemographic and health-related data from Italian residents who participated in the 2020 National Health and Wellness Survey (N = 10,026). To assess the characteristics and burden of chronic cough, adults who indicated that they had experienced chronic cough during the prior 12 months were compared with propensity score-matched controls without chronic cough.
RESULTS: The estimated weighted lifetime and 12-month prevalence of chronic cough were estimated as 9.2% and 6.3%, respectively. Compared with matched controls, respondents with chronic cough had significantly lower measures of overall physical and mental health (P < .001 for both comparisons), and significantly higher rates of anxiety, depression, and sleep disorders (P < .001 for all comparisons). Chronic cough was significantly associated with higher rates of impairment of work and other activities (P < .001 for all comparisons) in the past 7 days, any-cause emergency department visits and hospitalizations in the prior 6 months (P < .001 for both comparisons), and more visits to general and specialist health care providers (P < .001 for both comparisons) in the prior 6 months.
CONCLUSIONS: In Italy, chronic cough affects an estimated 3.3 million adults annually and represents a significant burden to individuals and the health care system.
CONCLUSIONS: Little is known about the prevalence of chronic cough in Italy. We found that, in Italy chronic cough represents a significant burden to individuals and the health care system, affecting an estimated 3.3 million adults annually.
摘要：
背景：慢性咳嗽与健康相关生活质量下降有关，对睡眠的负面影响，工作,和其他日常活动，和增加使用卫生保健资源。关于意大利慢性咳嗽的患病率知之甚少。在本研究中，我们试图估计意大利慢性咳嗽的患病率，描述与慢性咳嗽相关的社会人口统计学和临床特征，并描述慢性咳嗽对整体健康和健康的影响，工作和其他日常活动，和医疗保健资源的使用。
方法：我们进行了一项横断面研究，以收集参加2020年全国健康与保健调查的意大利居民的社会人口统计学和健康相关数据（N=10,026）。评估慢性咳嗽的特点和负担，将表示在之前12个月内经历过慢性咳嗽的成年人与没有慢性咳嗽的倾向评分匹配的对照进行比较.
结果：慢性咳嗽的估计加权寿命和12个月患病率估计为9.2％和6.3％，分别。与匹配的对照相比，慢性咳嗽的受访者的总体身体和心理健康指标明显较低（两种比较均P<.001），和显著更高的焦虑率，抑郁症,和睡眠障碍（所有比较P<.001）。在过去7天内，慢性咳嗽与较高的工作和其他活动受损率显著相关(所有比较P<.001)，前6个月的任何原因的急诊科就诊和住院（两个比较P<.001），和更多的访问一般和专科卫生保健提供者（P<.001为两个比较）前6个月。
结论：在意大利，慢性咳嗽每年影响约330万成年人，对个人和医疗保健系统构成重大负担。
结论：关于意大利慢性咳嗽的患病率知之甚少。我们发现,在意大利，慢性咳嗽对个人和医疗保健系统来说是一个巨大的负担，每年影响约330万成年人。
方法：我们进行了一项横断面研究，以收集参加2020年全国健康与保健调查的意大利居民的社会人口统计学和健康相关数据（N=10,026）。评估慢性咳嗽的特点和负担，将表示在之前12个月内经历过慢性咳嗽的成年人与没有慢性咳嗽的倾向评分匹配的对照进行比较.
结果：慢性咳嗽的估计加权寿命和12个月患病率估计为9.2％和6.3％，分别。与匹配的对照相比，慢性咳嗽的受访者的总体身体和心理健康指标明显较低（两种比较均P<.001），和显著更高的焦虑率，抑郁症,和睡眠障碍（所有比较P<.001）。在过去7天内，慢性咳嗽与较高的工作和其他活动受损率显著相关(所有比较P<.001)，前6个月的任何原因的急诊科就诊和住院（两个比较P<.001），和更多的访问一般和专科卫生保健提供者（P<.001为两个比较）前6个月。
结论：在意大利，慢性咳嗽每年影响约330万成年人，对个人和医疗保健系统构成重大负担。
结论：关于意大利慢性咳嗽的患病率知之甚少。我们发现,在意大利，慢性咳嗽对个人和医疗保健系统来说是一个巨大的负担，每年影响约330万成年人。
