Abstract：
Background: Oral graft-versus-host disease (GVHD) is characterized by mucosal lesions, salivary gland dysfunction etc., accompanied by pain and oral dysfunction. The efficacy of photobiomodulation (PBM) in managing pain and inflammation has been demonstrated. PBM has been applied in oral GVHD and is regarded as a potent adjunctive therapy. Objective: To review the application of PBM for oral GVHD and summarize its biological mechanisms and recommended parameters. Materials and Methods: The article provides an overview of the therapeutic effects of PBM in oral GVHD cases. It analyzes the biological mechanisms from different aspects and explores the potential prospects of PBM, and appropriate parameters and frequency for GVHD are recommended. Conclusions: The efficacy of PBM in oral GVHD has been demonstrated through symptom alleviation and function improvement. It is recommended as an adjuvant therapy for oral GVHD. However, further research is required to explore optimal devices, parameters, and potential complications associated with using PBM in oral GVHD.
摘要：
背景:口腔移植物抗宿主病(GVHD)以粘膜病变为特征,唾液腺功能障碍等.,伴有疼痛和口腔功能障碍。已经证明了光生物调节(PBM)在控制疼痛和炎症中的功效。PBM已应用于口服GVHD，被认为是一种有效的辅助疗法。目的：综述PBM在口腔GVHD中的应用，总结其生物学机制和推荐参数。材料和方法：本文概述了PBM在口服GVHD病例中的治疗作用。它从不同方面分析了生物机制，并探讨了PBM的潜在前景。并建议GVHD的适当参数和频率。结论：PBM在口服GVHD中的疗效已通过症状缓解和功能改善得到证实。推荐作为口服GVHD的辅助治疗。然而,需要进一步的研究来探索最佳设备，参数,以及与在口服GVHD中使用PBM相关的潜在并发症。
