PDF(Pubmed)
Abstract：
Recent studies on classic psychedelics have suggested that their use is associated with psychological strengths and resilience, thereby conferring users a type of psychological protection relative to non-users. However, this idea has been brought into question by recent findings suggesting that lifetime users of lysergic acid diethylamide (LSD) report worse mental health during stressful experiences. The current study addresses these mixed findings by examining whether LSD use prior to a stressful experience buffers against the psychological distress experienced in the wake of the stressful experience. This study draws on openly-available data from the National Survey on Drug Use and Health (2008-2019) on 5,067,553 (weighted) unemployed, job seeking individuals experiencing job loss. Using purposeful respondent exclusion criteria to establish temporal precedence of the variables under investigation, this study offers a straightforward test of whether LSD use confers psychological resilience to naturalistic users. LSD use prior to job loss was associated with a higher likelihood of severe psychological distress following job loss, regardless of whether sociodemographic variables were controlled for or not. In sum, this study fails to find evidence for LSD-conferred psychological resilience in naturalistic users in the wake of a stressful experience.
摘要：
最近对经典迷幻药的研究表明，它们的使用与心理力量和韧性有关，从而赋予用户一种相对于非用户的心理保护。然而,最近的研究结果表明,麦角酸二乙酰胺(LSD)的终身使用者在紧张的经历期间报告的心理健康更差,这一观点受到了质疑.当前的研究通过检查在压力经历之前使用LSD是否可以缓冲压力经历后所经历的心理困扰来解决这些混合发现。这项研究借鉴了来自全国药物使用和健康调查（2008-2019）的公开数据，涉及5,067,553（加权）失业者，求职经历失业的个人。使用有目的的受访者排除标准来确定所调查变量的时间优先级，这项研究提供了一个简单的测试，即使用LSD是否会赋予自然使用者心理弹性。失业前使用LSD与失业后严重心理困扰的可能性更高相关，无论社会人口统计学变量是否得到控制。总之,这项研究未能找到证据证明自然主义使用者在经历紧张经历后具有LSD赋予的心理弹性.
