Abstract：
BACKGROUND: Pre-exposure prophylaxis (PrEP) against the human immunodeficiency virus (HIV) is an effective and safe preventive measure. However, it has not reached all target users who could benefit from it. The study aimed to understand the sociodemographic, clinical and behavioral baseline characteristics of PrEP users. As a secondary objective, the use of concomitant medication and drug consumption were described.
METHODS: Observational, retrospective and descriptive study of the sociodemographic, clinical and behavioral characteristics of the users who were included in the PrEP program of the Community of Madrid during the first two years of experience.
RESULTS: Two thousand two hundred fifty-six PrEP users were included, 99.0% men, with a mean age of 36.9 years (SD 8.68). 33.1% presented a sexually transmitted infection (STI) on the first visit, highlighting chlamydiasis and rectal gonococci. 70.4% reported using drugs associated with sex, and 42.4% participated in chemsex sessions in the last 3 months. A high percentage of users with concomitant medication was observed (37.6%), highlighting drugs related to mental health and alopecia.
CONCLUSIONS: A multidisciplinary approach is required to cover all the needs of PrEP users, including mental health evaluation measures and addiction treatment with the clinical approach.
METHODS: Observational, retrospective and descriptive study of the sociodemographic, clinical and behavioral characteristics of the users who were included in the PrEP program of the Community of Madrid during the first two years of experience.
RESULTS: Two thousand two hundred fifty-six PrEP users were included, 99.0% men, with a mean age of 36.9 years (SD 8.68). 33.1% presented a sexually transmitted infection (STI) on the first visit, highlighting chlamydiasis and rectal gonococci. 70.4% reported using drugs associated with sex, and 42.4% participated in chemsex sessions in the last 3 months. A high percentage of users with concomitant medication was observed (37.6%), highlighting drugs related to mental health and alopecia.
CONCLUSIONS: A multidisciplinary approach is required to cover all the needs of PrEP users, including mental health evaluation measures and addiction treatment with the clinical approach.
摘要：
背景：针对人类免疫缺陷病毒（HIV）的暴露前预防（PrEP）是一种有效且安全的预防措施。然而,它还没有达到所有可以从中受益的目标用户。这项研究旨在了解社会人口统计学，PrEP使用者的临床和行为基线特征。作为次要目标，描述了合并用药和药物消耗的使用情况.
方法：观察性，社会人口统计学的回顾性和描述性研究，在最初两年的经验中，被纳入马德里社区PrEP计划的用户的临床和行为特征。
结果：包括两千二百五十六个PrEP用户，99.0%男性,平均年龄36.9岁（SD8.68）。33.1%的人在首次就诊时出现性传播感染(STI),突出衣原体病和直肠淋球菌。70.4％的人报告使用与性行为有关的药物，在过去3个月中，有42.4％的人参加了Chemsex课程。观察到合并用药的使用者比例很高(37.6%)，强调与心理健康和脱发有关的药物。
结论：需要采用多学科方法来满足PrEP用户的所有需求，包括心理健康评估措施和成瘾治疗的临床方法。
方法：观察性，社会人口统计学的回顾性和描述性研究，在最初两年的经验中，被纳入马德里社区PrEP计划的用户的临床和行为特征。
结果：包括两千二百五十六个PrEP用户，99.0%男性,平均年龄36.9岁（SD8.68）。33.1%的人在首次就诊时出现性传播感染(STI),突出衣原体病和直肠淋球菌。70.4％的人报告使用与性行为有关的药物，在过去3个月中，有42.4％的人参加了Chemsex课程。观察到合并用药的使用者比例很高(37.6%)，强调与心理健康和脱发有关的药物。
结论：需要采用多学科方法来满足PrEP用户的所有需求，包括心理健康评估措施和成瘾治疗的临床方法。
