PDF(Pubmed)
Abstract：
Objectives: The objective of the study was to carry out an analysis of the methodological quality of clinical trials (effects of exercise on frailty in older people) based on ACSM recommendations. Methods: The search scope included PubMed, Embase, Web of Science, Cochrane, and literature that cannot be retrieved from the database. The topic was the impact of exercise on frailty in elderly people. Changes in five outcome measures (FP, BI, SPPB, GS, and BMI) were assessed using mean differences (MD) and 95% confidence intervals (95% CI). A random effects model (RE) was used to conduct a meta-analysis and compare the results between subgroups. Results: The intervention effects of exercise on the five outcome indicators of frailty in elderly people were all significant (p < 0.05). The effect of a high-consistency subgroup on outcome indicators FP and GS was more significant than that of the low- or uncertain-consistency subgroup (MD: -1.09 < -0.11, MD: 2.39 >1.1). There was no significant difference in the intervention effect as reflected in the outcome measures SPPB and BMI in the high-consistency subgroup (p = 0.07, p = 0.34). There was no significant difference in the impact of the intervention on the outcome measure BI between the two subgroups (p = 0.06, p = 0.14). Conclusions: Exercise prescriptions with high consistency with ACSM recommendations may be more effective in both FP and GS interventions than those with uncertain or low consistency. However, it is essential to note that the data derived from the meta-analysis is still subject to the small number of studies, the unknown degree of consistency of participants in individual studies, and the different mix of cases in the studies.
摘要：
目标：该研究的目的是根据ACSM建议对临床试验的方法学质量（运动对老年人虚弱的影响）进行分析。方法：搜索范围包括PubMed，Embase,WebofScience,科克伦,和无法从数据库中检索到的文献。主题是运动对老年人虚弱的影响。五项结果指标的变化(FP，BI,SPPB,GS,和BMI）使用均差（MD）和95％置信区间（95％CI）进行评估。使用随机效应模型（RE）进行荟萃分析，并比较亚组之间的结果。结果:运动对老年人体弱者五项结局指标的干预效果均有统计学意义(p<0.05)。高一致性亚组对结果指标FP和GS的影响比低一致性或不确定一致性亚组更显著(MD:-1.09<-0.11,MD:2.39>1.1)。高一致性亚组的结果指标SPPB和BMI反映的干预效果没有显着差异（p=0.07，p=0.34）。两个亚组之间干预对结果测量BI的影响没有显着差异（p=0.06，p=0.14）。结论：在FP和GS干预措施中，与ACSM建议高度一致的运动处方可能比不确定或一致性低的运动处方更有效。然而,值得注意的是，荟萃分析得出的数据仍然受到少量研究的影响，个体研究中参与者的一致性程度未知，以及研究中不同的病例组合。
