PDF(Pubmed)
Abstract：
BACKGROUND In various situations such as pain, exposure to hot or cold, and mental stress, where physiological stress occurs, the increased excitatory response in the sympathetic efferent neurons leads to an increased return of blood flow from the peripheral veins to the right atrium. The cold pressor test (CPT) is based on the effects of a cold stimulus that activates afferent sensory pathways to trigger a sympathetic response, resulting in an increase in blood pressure. This study aimed to evaluate the effects of the cold pressor test on popliteal vein diameter, flow velocity, and blood flow in the lower limbs in 60 healthy individuals. MATERIAL AND METHODS We included 30 men and 30 women age 18-40 years. Baseline vein diameter, flow velocity, and blood flow of the left popliteal vein were measured by Doppler ultrasound, then the left hand was immersed in a bucket of cold water. After immersing the hand in cold water for 1 minute (CPT-1), 3 measurements of vein diameter, flow velocity, and blood flow were taken again, and their averages were calculated. RESULTS In the study, data obtained from the individuals were statistically analyzed. At CPT-1, venous diameter and flow values showed significant increase compared to baseline (P=0.001, P<0.001, respectively). CONCLUSIONS In healthy volunteers, CPT increases venous flow in the popliteal veins. However, our study did not provide evidence for the hypothesis that the increase in venous return is due to venoconstriction mechanisms.
摘要：
背景技术在诸如疼痛的各种情况下,暴露于热或冷，和精神压力，发生生理压力的地方，交感神经传出神经元的兴奋反应增加导致从外周静脉到右心房的血流回流增加。冷加压测试（CPT）基于冷刺激的影响，该刺激激活传入的感觉通路以触发交感神经反应，导致血压升高。本研究旨在评估冷加压试验对the静脉直径的影响，流速,60名健康人的下肢血流。材料和方法我们包括30名18-40岁的男性和30名女性。基线静脉直径，流速,通过多普勒超声测量左the静脉的血流量，然后左手浸入一桶冷水中。将手浸入冷水中1分钟（CPT-1）后，3测量静脉直径，流速,血液再次流动，并计算了它们的平均值。结果在研究中，从个体获得的数据进行统计分析。在CPT-1时，静脉直径和流量值与基线相比显着增加（分别为P=0.001，P<0.001）。结论在健康志愿者中,CPT增加了the静脉的静脉流量。然而,我们的研究没有为静脉回流增加是由于静脉收缩机制的假设提供证据.
