Abstract：
The aim of this study was to assess, through a systematic review, the status of infrared thermography (IRT) as a diagnostic tool for skin neoplasms of the head and neck region and in order to validate its effectiveness in differentiating benign and malignant lesions. A search was carried out in the LILACS, PubMed/MEDLINE, SCOPUS, Web of Science and EMBASE databases including studies published between 2004 and 2024, written in the Latin-Roman alphabet. Accuracy studies with patients aged 18 years or over presenting benign and malignant lesions in the head and neck region that evaluated the performance of IRT in differentiating these lesions were included. Lesions of mesenchymal origin and studies that did not mention histopathological diagnosis were excluded. The systematic review protocol was registered in the PROSPERO database (CRD42023416079). Reviewers independently analyzed titles, abstracts, and full-texts. After extracting data, the risk of bias of the selected studies was assessed using the QUADAS - 2 tool. Results were narratively synthesized and the certainty of evidence was measured using the GRADE approach. The search resulted in 1,587 records and three studies were included. Only one of the assessed studies used static IRT, while the other two studies used cold thermal stress. All studies had an uncertain risk of bias. In general, studies have shown wide variation in the accuracy of IRT for differentiating between malignant and benign lesions, with a low level of certainty in the evidence for both specificity and sensitivity.
摘要：
这项研究的目的是评估，通过系统审查，红外热成像（IRT）作为头颈部皮肤肿瘤的诊断工具的地位，以验证其在鉴别良性和恶性病变方面的有效性。在LILACS中进行了搜索，PubMed/MEDLINE,Scopus,WebofScience和EMBASE数据库，包括2004年至2024年之间发表的研究，以拉丁罗马字母书写。包括对18岁或以上的患者进行的准确性研究，这些患者在头颈部区域表现出良性和恶性病变，以评估IRT在区分这些病变方面的表现。间充质起源的病变和未提及组织病理学诊断的研究被排除。系统评价方案在PROSPERO数据库(CRD42023416079)中注册。审稿人独立分析了标题，摘要,和全文。提取数据后，使用QUADAS-2工具评估所选研究的偏倚风险.对结果进行叙述合成，并使用GRADE方法测量证据的确定性。搜索产生了1,587条记录，并纳入了三项研究。只有一项评估研究使用静态IRT，而其他两项研究使用冷热应力。所有研究都有不确定的偏倚风险。总的来说,研究表明，IRT区分恶性和良性病变的准确性差异很大，特异性和敏感性证据的确定性较低。
