PDF(Pubmed)
Abstract：
UNASSIGNED: Chronic cough (CC) affects about 10% of adults, but opioid use in CC is not well understood.
UNASSIGNED: To determine the use of opioid-containing cough suppressant (OCCS) prescriptions in patients with CC using electronic health records.
UNASSIGNED: Retrospective cohort study.
UNASSIGNED: Through retrospective analysis of Midwestern U.S. electronic health records, diagnoses, prescriptions, and natural language processing identified CC - at least three medical encounters with cough, with 56-120 days between first and last encounter - and a \'non-chronic cohort\'. Student\'s t-test, Pearson\'s chi-square, and zero-inflated Poisson models were used.
UNASSIGNED: About 20% of 23,210 patients with CC were prescribed OCCS; odds of an OCCS prescription were twice as great in CC. In CC, OCCS drugs were ordered in 38% with Medicaid insurance and 15% with commercial insurance.
UNASSIGNED: Findings identify an important role for opioids in CC, and opportunity to learn more about the drugs\' effectiveness.
UNASSIGNED: To determine the use of opioid-containing cough suppressant (OCCS) prescriptions in patients with CC using electronic health records.
UNASSIGNED: Retrospective cohort study.
UNASSIGNED: Through retrospective analysis of Midwestern U.S. electronic health records, diagnoses, prescriptions, and natural language processing identified CC - at least three medical encounters with cough, with 56-120 days between first and last encounter - and a \'non-chronic cohort\'. Student\'s t-test, Pearson\'s chi-square, and zero-inflated Poisson models were used.
UNASSIGNED: About 20% of 23,210 patients with CC were prescribed OCCS; odds of an OCCS prescription were twice as great in CC. In CC, OCCS drugs were ordered in 38% with Medicaid insurance and 15% with commercial insurance.
UNASSIGNED: Findings identify an important role for opioids in CC, and opportunity to learn more about the drugs\' effectiveness.
摘要：
■慢性咳嗽（CC）影响约10％的成年人，但在CC中使用阿片类药物还没有得到很好的理解。
■使用电子健康记录确定CC患者使用含阿片类药物的止咳药（OCCS）处方的使用。
■回顾性队列研究。
■通过对美国中西部电子健康记录的回顾性分析，诊断,处方,和自然语言处理识别CC-至少三次咳嗽的医疗遭遇，在第一次和最后一次相遇之间有56-120天-和一个“非慢性队列”。学生t检验，皮尔森的卡方，并使用零膨胀泊松模型。
■23,210例CC患者中约有20％被处方OCCS；在CC中，OCCS处方的几率是其两倍。在CC中,OCCS药物的订购比例为38％，有Medicaid保险，有15％的商业保险。
■研究发现阿片类药物在CC中的重要作用，并有机会更多地了解药物的有效性。
■使用电子健康记录确定CC患者使用含阿片类药物的止咳药（OCCS）处方的使用。
■回顾性队列研究。
■通过对美国中西部电子健康记录的回顾性分析，诊断,处方,和自然语言处理识别CC-至少三次咳嗽的医疗遭遇，在第一次和最后一次相遇之间有56-120天-和一个“非慢性队列”。学生t检验，皮尔森的卡方，并使用零膨胀泊松模型。
■23,210例CC患者中约有20％被处方OCCS；在CC中，OCCS处方的几率是其两倍。在CC中,OCCS药物的订购比例为38％，有Medicaid保险，有15％的商业保险。
■研究发现阿片类药物在CC中的重要作用，并有机会更多地了解药物的有效性。
