Abstract：
Folate is an essential component of many metabolic processes, and folate deficiency is known to cause various disorders. Folate and folic acid, a synthetic and chemically stable form of folate, enriched diet are typically used to overcome this deficiency. Folic acid and folate however, are susceptible to harsh environment and folates enrichment using nanoparticles is an intensively studied strategy in food industry. This review highlights the current methods and types of matrices utilized to develop folic acid/folate carrying nanoparticles. The folic acid/folate loaded nanoparticles prevent cargo degradation during gut absorption and under harsh food processing conditions including, high temperatures, UV light, and autoclaving. The data demonstrates that nanofortifcation of folates using proteins and biopolymers effectively enhances the bioavailability of the cargo. The encapsulation of folic acid in biopolymers by emulsion, spray drying and ionic gelation represent simplistic methods that can be easily scaled up with applications in food industry.
摘要：
叶酸是许多代谢过程的重要组成部分，已知叶酸缺乏会导致各种疾病。叶酸和叶酸，叶酸的合成和化学稳定的形式，丰富的饮食通常用于克服这种缺陷。叶酸和叶酸，易受恶劣环境的影响，使用纳米颗粒富集叶酸是食品工业中深入研究的策略。这篇综述重点介绍了用于开发叶酸/叶酸纳米颗粒的当前方法和基质类型。负载叶酸/叶酸的纳米颗粒可防止肠道吸收过程中和苛刻的食品加工条件下的货物降解，包括，高温,UV光,还有高压灭菌.数据表明,使用蛋白质和生物聚合物的叶酸的纳米强化有效地增强了货物的生物利用度。通过乳液将叶酸包封在生物聚合物中，喷雾干燥和离子凝胶化是简单的方法，可以很容易地扩大在食品工业中的应用。
