Epidemic of parvovirus B19 and disease severity in pregnant people, Denmark, January to March 2024.

孕妇中细小病毒 B19 的流行和疾病的严重程度 ，丹麦,2024 年 1 月至 3 月。

• 影响指数: 21.286
• 发表时间: 2024 Jun
• 来源期刊: Euro Surveill
• DOI: 10.2807/1560-7917.ES.2024.29.24.2400299
• PMID: 38873795
• 文章类型: Journal Article
• 中科院分区: Q1
• 方向: 医学
• 作者列表: Nordholm AC,Trier Møller F,Fischer Ravn S,Flink Sørensen L,Moltke-Prehn A,Elskær Mollerup J,Funk T,Sperling L,Jeyaratnam U,Træholt Franck K,Hjort-Pedersen K,Hjørnet Kamper C,Thoft Nielsen R,Jokelainen P,Wessman M

关键词: Fifth disease; epidemiology; erythema infectiosum; parvovirus B19; pregnancy; public health; surveillance

Mesh: Humans; Female; Pregnancy; Denmark / epidemiology; Parvovirus B19, Human / isolation & purification; Pregnancy Complications, Infectious / epidemiology diagnosis virology; Adult; Incidence; Parvoviridae Infections / epidemiology diagnosis; Epidemics; Hydrops Fetalis / epidemiology virology; Severity of Illness Index; Young Adult; Erythema Infectiosum / epidemiology diagnosis; Adolescent; Abortion, Spontaneous / epidemiology virology; Population Surveillance

Abstract

We report an epidemic of parvovirus B19 infections in Denmark during the first quarter of 2024, with a peak incidence 3.5 times higher than during the most recent epidemic in 2017. In total, 20.1% (130/648) of laboratory-confirmed cases were pregnant. Severe adverse outcomes were observed among 12.3% (16/130) of pregnant people and included foetal anaemia, foetal hydrops and miscarriage. Parvovirus B19 infection is not systematically monitored, but a national laboratory-based surveillance system is currently being established in Denmark.

摘要

我们报告了2024年第一季度丹麦细小病毒B19感染的流行，其峰值发病率是2017年最近一次流行的3.5倍。总的来说,20.1%(130/648)的实验室确诊病例怀孕。在12.3%(16/130)的孕妇中观察到严重的不良结局，包括胎儿贫血，胎儿积水和流产。细小病毒B19感染没有系统监测，但是丹麦目前正在建立一个基于实验室的国家监测系统。