PDF(Pubmed)
Abstract：
BACKGROUND: Internet-based cognitive behavioral therapy (CBT) and stand-alone mindfulness meditation interventions are gaining empirical support for a wide variety of mental health conditions. In this study, we test the efficacy of web-based therapist-guided mindfulness-based cognitive behavioral therapy (CBT-M) for body dysmorphic disorder (BDD), a psychiatric disorder characterized by preoccupations with perceived defects in appearance.
OBJECTIVE: This study aims to determine whether CBT-M for BDD delivered on the web is feasible and acceptable and whether mindfulness meditation adds to CBT treatment effects for BDD.
METHODS: In this 8-week, 2-arm, parallel pilot randomized controlled trial, n=28 adults (aged between 18 and 55 years) were randomly allocated to an experimental group (web-based therapist-guided CBT-M) or a control group (web-based therapist-guided CBT). Study retention, accrual, and intervention adherence were assessed, along with self-report measures for BDD, depression, anxiety, and pain intensity taken at baseline and postintervention.
RESULTS: This study was feasible to implement and deemed acceptable by participants. After 8 weeks, significant improvements were found on all outcome measures for both treatment groups, and large between-group effect sizes favoring CBT-M were found for BDD symptom severity (d=-0.96), depression (d=-1.06), pain severity (d=-1.12), and pain interference (d=-1.28). However, linear mixed models demonstrated no significant differences between the groups over 8 weeks.
CONCLUSIONS: The results suggest that mindfulness meditation may add to beneficial web-based CBT treatment effects for BDD. An adequately powered randomized control trial of web-based CBT-M is warranted.
BACKGROUND: ClinicalTrials.gov NCT05402475, http://clinicaltrials.gov/ct2/show/NCT05402475.
OBJECTIVE: This study aims to determine whether CBT-M for BDD delivered on the web is feasible and acceptable and whether mindfulness meditation adds to CBT treatment effects for BDD.
METHODS: In this 8-week, 2-arm, parallel pilot randomized controlled trial, n=28 adults (aged between 18 and 55 years) were randomly allocated to an experimental group (web-based therapist-guided CBT-M) or a control group (web-based therapist-guided CBT). Study retention, accrual, and intervention adherence were assessed, along with self-report measures for BDD, depression, anxiety, and pain intensity taken at baseline and postintervention.
RESULTS: This study was feasible to implement and deemed acceptable by participants. After 8 weeks, significant improvements were found on all outcome measures for both treatment groups, and large between-group effect sizes favoring CBT-M were found for BDD symptom severity (d=-0.96), depression (d=-1.06), pain severity (d=-1.12), and pain interference (d=-1.28). However, linear mixed models demonstrated no significant differences between the groups over 8 weeks.
CONCLUSIONS: The results suggest that mindfulness meditation may add to beneficial web-based CBT treatment effects for BDD. An adequately powered randomized control trial of web-based CBT-M is warranted.
BACKGROUND: ClinicalTrials.gov NCT05402475, http://clinicaltrials.gov/ct2/show/NCT05402475.
摘要：
背景：基于互联网的认知行为疗法（CBT）和独立的正念冥想干预措施正在为各种心理健康状况提供经验支持。在这项研究中,我们测试了基于网络的治疗师指导的基于正念的认知行为疗法（CBT-M）对身体畸形障碍（BDD）的疗效，一种精神病，其特征是关注外观上的缺陷。
目的：本研究旨在确定网络上提供的BDD的CBT-M是否可行和可接受，以及正念冥想是否会增加BDD的CBT治疗效果。
方法：在这8周，双臂，平行先导随机对照试验，n=28名成年人（年龄在18至55岁之间）被随机分配到实验组（基于网络的治疗师指导的CBT-M）或对照组（基于网络的治疗师指导的CBT）。研究保留，应计，并评估干预依从性，以及BDD的自我报告措施，抑郁症,焦虑,以及基线和干预后的疼痛强度。
结果：这项研究是可行的，并且被参与者认为是可以接受的。8周后,两个治疗组的所有结局指标均有显着改善，发现BDD症状严重程度有利于CBT-M的大组间效应大小(d=-0.96)，抑郁症（d=-1.06），疼痛严重程度（d=-1.12），和疼痛干扰（d=-1.28）。然而,线性混合模型在8周内显示两组间无显著差异.
结论：结果表明，正念冥想可能会增加BDD基于网络的CBT治疗效果。基于网络的CBT-M的充分授权的随机对照试验是必要的。
背景：ClinicalTrials.govNCT05402475，http://clinicaltrials.gov/ct2/show/NCT05402475。
目的：本研究旨在确定网络上提供的BDD的CBT-M是否可行和可接受，以及正念冥想是否会增加BDD的CBT治疗效果。
方法：在这8周，双臂，平行先导随机对照试验，n=28名成年人（年龄在18至55岁之间）被随机分配到实验组（基于网络的治疗师指导的CBT-M）或对照组（基于网络的治疗师指导的CBT）。研究保留，应计，并评估干预依从性，以及BDD的自我报告措施，抑郁症,焦虑,以及基线和干预后的疼痛强度。
结果：这项研究是可行的，并且被参与者认为是可以接受的。8周后,两个治疗组的所有结局指标均有显着改善，发现BDD症状严重程度有利于CBT-M的大组间效应大小(d=-0.96)，抑郁症（d=-1.06），疼痛严重程度（d=-1.12），和疼痛干扰（d=-1.28）。然而,线性混合模型在8周内显示两组间无显著差异.
结论：结果表明，正念冥想可能会增加BDD基于网络的CBT治疗效果。基于网络的CBT-M的充分授权的随机对照试验是必要的。
背景：ClinicalTrials.govNCT05402475，http://clinicaltrials.gov/ct2/show/NCT05402475。
