关键词: CA-MRSA Purulent lymphadenitis multiple drug resistance

Mesh : Humans Female Lymphadenitis / microbiology Methicillin-Resistant Staphylococcus aureus / isolation & purification genetics Staphylococcal Infections / microbiology diagnosis drug therapy Community-Acquired Infections / microbiology Infant China Genotype Lymph Nodes / microbiology pathology Infant, Newborn

来  源:   DOI:10.3855/jidc.18798

Abstract:
BACKGROUND: Methicillin-resistant Staphylococcus aureus (CA-MRSA), which has the potential to produce serious infections, was a common cause of skin and soft tissue infections, acute purulent lymphadenitis was rare.
METHODS: The patient was a female infant with lumps, tenderness, and fever on the right side of the neck and groin. Laboratory tests suggested a bacterial infection. The diagnosis of acute purulent lymphadenitis was made based on the clinical signs and the results of a supporting exam. After three days, MRSA developed in the secretions of suppurative lymph nodes. Her mother\'s nasopharyngeal swab sample results revealed MRSA. The genotypes of two bacterial strains that underwent molecular analysis were identical.
RESULTS: 17 days after admission, the patient showed signs of clinical recovery.
CONCLUSIONS: The incident brought to light the possible spread of CA-MRSA in the Chinese population. Even without a definite path of infection, CA-MRSA should be taken into consideration when the standard treatment for children with acute purulent lymphadenitis is ineffective. Early infancy MRSA acquisition may be mostly caused by maternal-infant horizontal transmission.
摘要:
背景:耐甲氧西林金黄色葡萄球菌(CA-MRSA),有可能产生严重的感染,是皮肤和软组织感染的常见原因,急性化脓性淋巴结炎罕见。
方法:患者是一个有肿块的女婴,压痛,右侧颈部和腹股沟发热.实验室检查提示细菌感染。根据临床体征和辅助检查的结果,对急性化脓性淋巴结炎进行了诊断。三天后,化脓性淋巴结分泌物中出现MRSA。她母亲的鼻咽拭子样本结果显示MRSA。进行分子分析的两种细菌菌株的基因型相同。
结果:入院后17天,患者出现临床康复迹象.
结论:该事件揭示了CA-MRSA在中国人群中的可能传播。即使没有明确的感染途径,当急性化脓性淋巴结炎患儿的标准治疗无效时,应考虑CA-MRSA。婴儿期早期MRSA的获得可能主要是由母婴水平传播引起的。
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