PDF(Pubmed)
Abstract：
UNASSIGNED: Gestational diabetes mellitus (GDM), a chronic condition leading to glucose intolerance during pregnancy, is common in low- and middle-income countries, posing health risks to both the mother and fetus. Limited studies have been done in Ethiopia, especially using WHO\'s 2013 universal screening criteria. Therefore, this study aimed to evaluate the risk factors linked to GDM in women attending antenatal (ANC) clinics in Hawassa town public health institutions, located in the Sidama regional state of Ethiopia.
UNASSIGNED: An Unmatched case-control study was carried out in Ethiopia\'s Sidama Region from April 1st to June 10th, 2023, involving 510 pregnant women. The Oral Glucose Tolerance Test (OGTT) was utilized for universal screening and diagnosing GDM based on the updated 2013 WHO diagnostic criteria. Data analysis included descriptive and analytical statistics, with variables having p-values below 0.1 deemed suitable for bivariate analysis. Statistical significance was assessed using the adjusted odds ratio (AOR) with a 95% confidence interval and a p-value < 0.05.
UNASSIGNED: The study involved 633 participants (255 cases and 378 controls), resulting in a 100% response rate, with women having an average age of 29.03 years.Variables such as: age at first conception (AOR=0.97, P=0.01, 95% CI (0.95,0.99)), urban residency (AOR=1.66, P<0.01, 95% CI(01.14,2.40)), widowed marital status (AOR=0.30, P=0.02, 95% CI (0.30,0.90)), parity (AOR=1.10, P<0.01, 95% CI (1.03,1.17)), history of stillbirth (AOR=1.15, P=0.03, 95% CI(1.04,2.30)), and previous cesarean section (AOR=1.86, P=0.01, 95% CI (1.13,2.66)) were identified as independent factors associated with GDM.
UNASSIGNED: The study concluded that factors like age at first conception, place of residence, marital status, parity, history of Caesarian section, and stillbirth were independently associated with GDM. Surprisingly, upper arm circumference (MUAC), a proxy for pre-gestational BMI, was not identified as a risk factor for GDM. It is recommended that healthcare providers conduct comprehensive GDM risk assessments in pregnant women to identify and address risk factors, and propose specific screening and intervention strategies.
UNASSIGNED: An Unmatched case-control study was carried out in Ethiopia\'s Sidama Region from April 1st to June 10th, 2023, involving 510 pregnant women. The Oral Glucose Tolerance Test (OGTT) was utilized for universal screening and diagnosing GDM based on the updated 2013 WHO diagnostic criteria. Data analysis included descriptive and analytical statistics, with variables having p-values below 0.1 deemed suitable for bivariate analysis. Statistical significance was assessed using the adjusted odds ratio (AOR) with a 95% confidence interval and a p-value < 0.05.
UNASSIGNED: The study involved 633 participants (255 cases and 378 controls), resulting in a 100% response rate, with women having an average age of 29.03 years.Variables such as: age at first conception (AOR=0.97, P=0.01, 95% CI (0.95,0.99)), urban residency (AOR=1.66, P<0.01, 95% CI(01.14,2.40)), widowed marital status (AOR=0.30, P=0.02, 95% CI (0.30,0.90)), parity (AOR=1.10, P<0.01, 95% CI (1.03,1.17)), history of stillbirth (AOR=1.15, P=0.03, 95% CI(1.04,2.30)), and previous cesarean section (AOR=1.86, P=0.01, 95% CI (1.13,2.66)) were identified as independent factors associated with GDM.
UNASSIGNED: The study concluded that factors like age at first conception, place of residence, marital status, parity, history of Caesarian section, and stillbirth were independently associated with GDM. Surprisingly, upper arm circumference (MUAC), a proxy for pre-gestational BMI, was not identified as a risk factor for GDM. It is recommended that healthcare providers conduct comprehensive GDM risk assessments in pregnant women to identify and address risk factors, and propose specific screening and intervention strategies.
摘要：
■妊娠期糖尿病（GDM），导致怀孕期间葡萄糖不耐受的慢性病，在低收入和中等收入国家很常见，对母亲和胎儿都有健康风险。在埃塞俄比亚进行了有限的研究，特别是使用世界卫生组织2013年的通用筛查标准。因此,这项研究旨在评估在Hawassa镇公共卫生机构的产前（ANC）诊所就诊的女性中与GDM相关的危险因素，位于埃塞俄比亚的Sidama地区。
4月1日至6月10日在埃塞俄比亚西达玛地区进行了一项无与伦比的病例对照研究，2023年，涉及510名孕妇。口服葡萄糖耐量试验（OGTT）用于基于更新的2013年WHO诊断标准的通用筛查和诊断GDM。数据分析包括描述性和分析性统计数据，P值低于0.1的变量被认为适合双变量分析。使用校正比值比(AOR)以95%置信区间和p值<0.05评估统计学显著性。
■该研究涉及633名参与者（255例病例和378名对照），导致100%的反应率，女性平均年龄为29.03岁。变量如：首次受孕年龄(AOR=0.97，P=0.01，95%CI(0.95，0.99))，城市居民(AOR=1.66，P<0.01，95%CI(01.14,2.40))，丧偶婚姻状况(AOR=0.30,P=0.02,95%CI(0.30,0.90)),平价(AOR=1.10，P<0.01，95%CI(1.03,1.17))，死产史（AOR=1.15，P=0.03，95%CI（1.04,2.30）），和既往剖宫产（AOR=1.86，P=0.01，95％CI（1.13，2.66））被确定为与GDM相关的独立因素。
■研究得出的结论是，初次受孕时的年龄等因素，居住地,婚姻状况,奇偶校验，剖腹产的历史，死产与GDM独立相关。令人惊讶的是,上臂圆周(MUAC),孕前BMI的代表，未被确定为GDM的危险因素。建议医疗保健提供者对孕妇进行全面的GDM风险评估，以识别和解决风险因素，并提出具体的筛查和干预策略。
4月1日至6月10日在埃塞俄比亚西达玛地区进行了一项无与伦比的病例对照研究，2023年，涉及510名孕妇。口服葡萄糖耐量试验（OGTT）用于基于更新的2013年WHO诊断标准的通用筛查和诊断GDM。数据分析包括描述性和分析性统计数据，P值低于0.1的变量被认为适合双变量分析。使用校正比值比(AOR)以95%置信区间和p值<0.05评估统计学显著性。
■该研究涉及633名参与者（255例病例和378名对照），导致100%的反应率，女性平均年龄为29.03岁。变量如：首次受孕年龄(AOR=0.97，P=0.01，95%CI(0.95，0.99))，城市居民(AOR=1.66，P<0.01，95%CI(01.14,2.40))，丧偶婚姻状况(AOR=0.30,P=0.02,95%CI(0.30,0.90)),平价(AOR=1.10，P<0.01，95%CI(1.03,1.17))，死产史（AOR=1.15，P=0.03，95%CI（1.04,2.30）），和既往剖宫产（AOR=1.86，P=0.01，95％CI（1.13，2.66））被确定为与GDM相关的独立因素。
■研究得出的结论是，初次受孕时的年龄等因素，居住地,婚姻状况,奇偶校验，剖腹产的历史，死产与GDM独立相关。令人惊讶的是,上臂圆周(MUAC),孕前BMI的代表，未被确定为GDM的危险因素。建议医疗保健提供者对孕妇进行全面的GDM风险评估，以识别和解决风险因素，并提出具体的筛查和干预策略。
