UNASSIGNED: A retrospective, multicentric study was conducted, and we analyzed all consecutive patients with CRLMs who underwent ALPPS over the eight-year period. Patients were categorized into two groups based on the type of resection-right trisectionectomy (ERH) or right hemihepatectomy (RH) respectively. The degree of hypertrophy (DH), its correlation with FLR and postoperative outcomes were assessed.
UNASSIGNED: The cohort consisted of 136 patients (72 in the ERH group and 64 in the RH group). Baseline characteristics, hypertrophy interval, and total liver volume showed no significant differences between the groups. DH was greater in the ERH group (83.2% vs. 62.5%, p = 0.025). A strong negative correlation was observed between FLR volume and DH in both groups. Postoperative outcomes and one-year survival were comparable between the groups.
UNASSIGNED: FLR hypertrophy is influenced by the localization of the liver transection line in ALPPS. Furthermore, correlation analysis indicated that a smaller estimated FLR is associated with greater DH. No statistical difference in outcomes was noted between the groups.
■回顾,进行了多中心研究,我们分析了所有连续8年接受ALPPS治疗的CRLM患者.根据切除类型将患者分为两组,分别为右三节切除术(ERH)或右半肝切除术(RH)。肥大程度(DH),评估其与FLR和术后结局的相关性.
■该队列包括136名患者(ERH组72名,RH组64名)。基线特征,肥大间隔,和总肝脏体积显示两组之间没有显着差异。DH在ERH组中更高(83.2%vs.62.5%,p=0.025)。在两组中,FLR体积与DH之间均呈强负相关。术后结局和一年生存率在两组之间具有可比性。
■FLR肥大受ALPPS中肝脏横切线定位的影响。此外,相关分析表明,较小的估计FLR与较大的DH相关。两组之间的结果无统计学差异。