PDF(Pubmed)
Abstract：
UNASSIGNED: Depression and impulsivity are etiologically linked to alcohol dependence (AD) and are known to affect course and outcomes. The relationship between impulsivity and depressive symptoms has been investigated only in a few studies of individuals with AD.
UNASSIGNED: This study aimed to explore the association between impulsivity and depressive symptoms in patients with AD.
UNASSIGNED: Our study was conducted in the inpatient setup of a tertiary care psychiatry institute. The study design is cross-sectional. The Barratt Impulsiveness Scale (BIS-11) and stop signal task (SST) were used to assess levels of global impulsivity and behavioral impulsivity, respectively, among 60 recently detoxified inpatients with AD. The Hamilton Depression Rating Scale (HAM-D) was used to measure depressive symptoms. The results were analyzed to examine the association of depressive symptoms with impulsivity. Pearson\'s coefficient of correlation or Spearman\'s rank correlation and linear regression analysis were performed to explore the association between quantitative variables.
UNASSIGNED: Patients with higher HAM-D scores were found to have significantly higher score on all three subscales of the BIS-11. The attention impulsivity subscale had the strongest correlations (r = 0.53, P < 0.001). Depressive symptoms were more strongly correlated with cognitive impulsivity (r = 0.54, P< 0.0001) compared with motor impulsivity and were not significantly associated with behavioral impulsivity. Adjusting for other variables, cognitive impulsivity was found to be the strongest predictor of the severity of depressive symptoms.
UNASSIGNED: The study showed a strong association between impulsivity and depressive symptoms in individuals with AD. This relationship may apply more to cognitive impulsivity, reflecting the role of impulsive decisions compared with impulsive actions.
UNASSIGNED: This study aimed to explore the association between impulsivity and depressive symptoms in patients with AD.
UNASSIGNED: Our study was conducted in the inpatient setup of a tertiary care psychiatry institute. The study design is cross-sectional. The Barratt Impulsiveness Scale (BIS-11) and stop signal task (SST) were used to assess levels of global impulsivity and behavioral impulsivity, respectively, among 60 recently detoxified inpatients with AD. The Hamilton Depression Rating Scale (HAM-D) was used to measure depressive symptoms. The results were analyzed to examine the association of depressive symptoms with impulsivity. Pearson\'s coefficient of correlation or Spearman\'s rank correlation and linear regression analysis were performed to explore the association between quantitative variables.
UNASSIGNED: Patients with higher HAM-D scores were found to have significantly higher score on all three subscales of the BIS-11. The attention impulsivity subscale had the strongest correlations (r = 0.53, P < 0.001). Depressive symptoms were more strongly correlated with cognitive impulsivity (r = 0.54, P< 0.0001) compared with motor impulsivity and were not significantly associated with behavioral impulsivity. Adjusting for other variables, cognitive impulsivity was found to be the strongest predictor of the severity of depressive symptoms.
UNASSIGNED: The study showed a strong association between impulsivity and depressive symptoms in individuals with AD. This relationship may apply more to cognitive impulsivity, reflecting the role of impulsive decisions compared with impulsive actions.
摘要：
■抑郁和冲动性在病因上与酒精依赖（AD）有关，并且已知会影响病程和结果。仅在少数AD患者的研究中研究了冲动与抑郁症状之间的关系。
■本研究旨在探讨AD患者的冲动性与抑郁症状之间的关系。
■我们的研究是在三级护理精神病学研究所的住院患者中进行的。研究设计是横断面的。使用Barratt冲动量表（BIS-11）和停止信号任务（SST）评估全球冲动和行为冲动的水平，分别,在60名最近戒毒的AD住院患者中。汉密尔顿抑郁量表（HAM-D）用于测量抑郁症状。分析结果以检查抑郁症状与冲动的关系。采用Pearson相关系数或Spearman秩相关和线性回归分析探讨定量变量之间的关联。
■发现HAM-D评分较高的患者在BIS-11的所有三个子量表上的评分均显着较高。注意冲动性分量表相关性最强(r=0.53,P<0.001)。与运动冲动相比，抑郁症状与认知冲动更密切相关（r=0.54，P<0.0001），与行为冲动无关。调整其他变量，认知冲动是抑郁症状严重程度的最强预测因子.
■该研究表明，在AD患者中，冲动性和抑郁症状之间存在很强的关联。这种关系可能更适用于认知冲动，反映冲动决策与冲动行为相比的作用。
■本研究旨在探讨AD患者的冲动性与抑郁症状之间的关系。
■我们的研究是在三级护理精神病学研究所的住院患者中进行的。研究设计是横断面的。使用Barratt冲动量表（BIS-11）和停止信号任务（SST）评估全球冲动和行为冲动的水平，分别,在60名最近戒毒的AD住院患者中。汉密尔顿抑郁量表（HAM-D）用于测量抑郁症状。分析结果以检查抑郁症状与冲动的关系。采用Pearson相关系数或Spearman秩相关和线性回归分析探讨定量变量之间的关联。
■发现HAM-D评分较高的患者在BIS-11的所有三个子量表上的评分均显着较高。注意冲动性分量表相关性最强(r=0.53,P<0.001)。与运动冲动相比，抑郁症状与认知冲动更密切相关（r=0.54，P<0.0001），与行为冲动无关。调整其他变量，认知冲动是抑郁症状严重程度的最强预测因子.
■该研究表明，在AD患者中，冲动性和抑郁症状之间存在很强的关联。这种关系可能更适用于认知冲动，反映冲动决策与冲动行为相比的作用。
