■本研究旨在阐明保定市某专科医院住院精神分裂症患者酒精使用障碍(AUDs)的相关危险因素,中国。
■这项横断面调查包括301名合并症患者。使用三个二元逻辑回归模型来研究精神分裂症患者与AUDs相关的因素。进行倾向得分匹配分析以验证回归模型识别的不一致变量。
■在性别方面,合并症组和非合并症组之间存在显着差异(P<.001),处置(P=.049),吸烟习惯(P<.001),居住地(P=.010),家庭关系(P=0.002),精神障碍家族史(P=.008),酗酒史(P=.003),发病潜伏期(P=0.005),冲动性(P<.001),自杀或自伤史(P<.001),单因素分析中明显的攻击行为(P<.001)。三个回归模型的曲线下面积值分别为0.83(P<.001),0.80(P<.001),和0.81(P<.001),分别。二元逻辑回归和倾向得分匹配分析表明,内向倾向,吸烟,急性发作,冲动,自杀或自伤史是与住院精神分裂症患者AUDs相关的独立危险因素,比值比>1。
■性格内向,吸烟,急性发作,冲动,住院精神分裂症患者的自杀或自伤史与AUDs独立相关。未来的研究应优先考虑纵向研究,以辨别潜在混杂风险因素的演变动态。
UNASSIGNED: This study aimed to elucidate the risk factors associated with alcohol use disorders (AUDs) among inpatients with schizophrenia at a specialized mental hospital in Baoding city, China.
UNASSIGNED: This cross-sectional survey comprised 301 comorbid patients. Three binary logistic regression models were used to investigate the factors linked to AUDs in patients with schizophrenia. Propensity score matching analysis was conducted to validate inconsistent variables identified by the regression models.
UNASSIGNED: Significant differences were observed between the comorbid and non-comorbid groups concerning sex (P < .001), disposition (P = .049), smoking habits (P < .001), place of residence (P = .010), family relationships (P = .002), family history of mental disorders (P = .008), history of alcoholism (P = .003), onset latency (P = .005), impulsivity (P < .001), suicide or self-injury history (P < .001), and obvious aggressive behavior (P < .001) in univariate analyses. The area under the curve values for the three regression models were 0.83 (P < .001), 0.80 (P < .001), and 0.81 (P < .001), respectively. Binary logistic regression and propensity score matching analyses indicated that introverted disposition, smoking, acute onset, impulsivity, and suicide or self-injury history were independent risk factors associated with AUDs in inpatients with schizophrenia with an odds ratio of > 1.
UNASSIGNED: Introverted disposition, smoking, acute onset, impulsivity, and suicide or self-injury history were independently associated with the AUDs in inpatients with schizophrenia. Future studies should prioritize longitudinal studies to discern the evolving dynamics of potential confounding risk factors.