关键词: LTP cognitive disorders learning long-term depression long-term potentiation memory synaptic plasticity

Mesh : Long-Term Potentiation / physiology Humans Animals History, 20th Century Learning Memory / physiology History, 21st Century

来  源:   DOI:10.1098/rstb.2023.0218   PDF(Pubmed)

Abstract:
We introduce and summarize reviews and research papers by speakers at a discussion meeting on \'Long-term potentiation: 50 years on\' held at the Royal Society, London, on 20-21 November 2023. The meeting followed earlier discussion meetings marking the 30th and 40th anniversaries of the discovery of long-term potentiation. These new contributions give an overview of current research and controversies in a vibrant branch of neuroscience with important implications for our understanding of the neurobiological basis of many forms of learning and memory and a wide spectrum of neurological and cognitive disorders.This article is part of a discussion meeting issue \'Long-term potentiation: 50 years on\'.
摘要:
我们在皇家学会举行的关于“长期增强:50年后”的讨论会议上介绍并总结了演讲者的评论和研究论文,伦敦,2023年11月20日至21日会议是在较早的讨论会议之后举行的,这标志着长期增强发现的30周年和40周年。这些新的贡献概述了神经科学充满活力的分支中的当前研究和争议,对我们理解许多形式的学习和记忆以及广泛的神经和认知障碍的神经生物学基础具有重要意义。本文是讨论会议问题“长期增强:50年后”的一部分。
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