Abstract：
UNASSIGNED: To report the clinical course and the retinal imaging features of a case of cytology-proven primary vitreoretinal lymphoma (PVRL) presenting with a transient bacillary layer detachment (BALAD) during the disease course.
UNASSIGNED: Observational case report.
UNASSIGNED: A 50 year-old woman was referred to us with a 2-month history of vitritis in both eyes, poorly responding to oral prednisolone. After discontinuation of oral prednisolone, worsening of vitritis and the appearance of multiple creamy-like subretinal infiltrates in the mid-peripheral retina of both eyes, along with the exclusion of common causes of intermediate/posterior uveitis, made us consider PVRL. Aqueous humor sampling detected MYD88 L265P mutation, and subsequent diagnostic pars plana vitrectomy in the left eye yielded a positive cytology for large B cell lymphoma consistent with PVRL. During the disease course, optical coherence tomography of the macula showed a BALAD in the right eye, which resolved during follow-up.
UNASSIGNED: Our case indicates that BALAD is a possible rare manifestation of PVRL, and this should be considered in the differential diagnosis process in order to avoid diagnostic delays.
UNASSIGNED: Observational case report.
UNASSIGNED: A 50 year-old woman was referred to us with a 2-month history of vitritis in both eyes, poorly responding to oral prednisolone. After discontinuation of oral prednisolone, worsening of vitritis and the appearance of multiple creamy-like subretinal infiltrates in the mid-peripheral retina of both eyes, along with the exclusion of common causes of intermediate/posterior uveitis, made us consider PVRL. Aqueous humor sampling detected MYD88 L265P mutation, and subsequent diagnostic pars plana vitrectomy in the left eye yielded a positive cytology for large B cell lymphoma consistent with PVRL. During the disease course, optical coherence tomography of the macula showed a BALAD in the right eye, which resolved during follow-up.
UNASSIGNED: Our case indicates that BALAD is a possible rare manifestation of PVRL, and this should be considered in the differential diagnosis process in order to avoid diagnostic delays.
摘要：
■报告一例经细胞学证实的原发性玻璃体视网膜淋巴瘤（PVRL）在病程中出现一过性菌层脱离（BALAD）的临床病程和视网膜影像学特征。
■观察性病例报告。
■一位50岁的女性被转诊给我们，双眼均有2个月的玻璃体炎病史，口服泼尼松龙反应不佳。停用口服泼尼松龙后,玻璃体炎恶化，双眼中周边视网膜出现多个乳脂状视网膜下浸润，除了排除中/后葡萄膜炎的常见原因，让我们考虑PVRL。房水采样检测到MYD88L265P突变，随后在左眼进行的诊断性玻璃体切割术对与PVRL一致的大B细胞淋巴瘤进行了细胞学检查。在疾病过程中，黄斑的光学相干断层扫描显示右眼有BALAD，在后续行动中解决了。
■我们的案例表明BALAD是PVRL的一种可能的罕见表现，在鉴别诊断过程中应考虑这一点,以避免诊断延迟.
■观察性病例报告。
■一位50岁的女性被转诊给我们，双眼均有2个月的玻璃体炎病史，口服泼尼松龙反应不佳。停用口服泼尼松龙后,玻璃体炎恶化，双眼中周边视网膜出现多个乳脂状视网膜下浸润，除了排除中/后葡萄膜炎的常见原因，让我们考虑PVRL。房水采样检测到MYD88L265P突变，随后在左眼进行的诊断性玻璃体切割术对与PVRL一致的大B细胞淋巴瘤进行了细胞学检查。在疾病过程中，黄斑的光学相干断层扫描显示右眼有BALAD，在后续行动中解决了。
■我们的案例表明BALAD是PVRL的一种可能的罕见表现，在鉴别诊断过程中应考虑这一点,以避免诊断延迟.
