%0 Journal Article
%T Transient Bacillary Layer Detachment During the Disease Course of Primary Vitreoretinal Lymphoma.
%A Casalino G
%A Malerba A
%A Fabris S
%A Bolli N
%A Croci GA
%A Pellegrini M
%A Rossi FG
%A Mapelli C
%A Viola F
%J Ocul Immunol Inflamm
%V 0
%N 0
%D 2024 Jun 5
%M 38838286
%F 3.728
%R 10.1080/09273948.2024.2359627
%X <B>UNASSIGNED: </B>To report the clinical course and the retinal imaging features of a case of cytology-proven primary vitreoretinal lymphoma (PVRL) presenting with a transient bacillary layer detachment (BALAD) during the disease course.<BR><B>UNASSIGNED: </B>Observational case report.<BR><B>UNASSIGNED: </B>A 50 year-old woman was referred to us with a 2-month history of vitritis in both eyes, poorly responding to oral prednisolone. After discontinuation of oral prednisolone, worsening of vitritis and the appearance of multiple creamy-like subretinal infiltrates in the mid-peripheral retina of both eyes, along with the exclusion of common causes of intermediate/posterior uveitis, made us consider PVRL. Aqueous humor sampling detected MYD88 L265P mutation, and subsequent diagnostic pars plana vitrectomy in the left eye yielded a positive cytology for large B cell lymphoma consistent with PVRL. During the disease course, optical coherence tomography of the macula showed a BALAD in the right eye, which resolved during follow-up.<BR><B>UNASSIGNED: </B>Our case indicates that BALAD is a possible rare manifestation of PVRL, and this should be considered in the differential diagnosis process in order to avoid diagnostic delays.