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Abstract：
BACKGROUND: The epidemiology of scabies is poorly understood, particularly in regions with high disease burden. This lack of epidemiological data, especially in sub-Saharan Africa, hampers the control and preventative measures. This study is aimed at estimating the prevalence and associated risk factors of scabies and impetigo in the Nata and Sowa catchment areas of Tutume district.
METHODS: A cross-sectional study was conducted in the Tutume District, targeting the settlements of Manxhotae, Malelejwe, Ndutshaa, and Tshwaane. Participants were randomly selected from households in the settlements. Data were collected using questionnaires, and participants were classified as having scabies typical lesions if they met criteria B and or C of International Alliance for the Control of Scabies (IACS) consensus criteria. Statistical significance was set at p<0.05, with a 95% confidence interval for precision.
RESULTS: A total of 429 participants were enrolled across the four settlements. The overall prevalence of scabies was found to be 18.18% (95%CI 14.8-22.1). The highest prevalence of scabies was in Manxhotae at 27.1% (95%CI 21.2-34.0) and Ndutshaa at 23.4% (95%CI 13.4-37.3). Malelejwe and Tshwaane had lower prevalence of 10.4% (95%CI 6.2-16.8) and 3.4% (95%CI 0.8-12.7), respectively. Only five (5) cases of impetigo were identified. Multivariable logistic regression analysis revealed that younger age of 0-4 years, 5-18 years and a household member with an itch were strongly associated with scabies, with adjusted odds ratios (aOR) of 7.9 (95%CI 2.4-25.6) p-value 0.001, 5.7(95%CI 2.7-11.7), p-value 0.001 and 14.3(95%CI 5.3-38.5) p-value 0.001 respectively.
CONCLUSIONS: The prevalence of scabies in the Nata catchment area was noted to be high. The risk factors included younger age, a household member with an itch, and less frequent bathing. Prospective studies are needed to explore household disease transmission dynamics and risk factors specific to the youth.
METHODS: A cross-sectional study was conducted in the Tutume District, targeting the settlements of Manxhotae, Malelejwe, Ndutshaa, and Tshwaane. Participants were randomly selected from households in the settlements. Data were collected using questionnaires, and participants were classified as having scabies typical lesions if they met criteria B and or C of International Alliance for the Control of Scabies (IACS) consensus criteria. Statistical significance was set at p<0.05, with a 95% confidence interval for precision.
RESULTS: A total of 429 participants were enrolled across the four settlements. The overall prevalence of scabies was found to be 18.18% (95%CI 14.8-22.1). The highest prevalence of scabies was in Manxhotae at 27.1% (95%CI 21.2-34.0) and Ndutshaa at 23.4% (95%CI 13.4-37.3). Malelejwe and Tshwaane had lower prevalence of 10.4% (95%CI 6.2-16.8) and 3.4% (95%CI 0.8-12.7), respectively. Only five (5) cases of impetigo were identified. Multivariable logistic regression analysis revealed that younger age of 0-4 years, 5-18 years and a household member with an itch were strongly associated with scabies, with adjusted odds ratios (aOR) of 7.9 (95%CI 2.4-25.6) p-value 0.001, 5.7(95%CI 2.7-11.7), p-value 0.001 and 14.3(95%CI 5.3-38.5) p-value 0.001 respectively.
CONCLUSIONS: The prevalence of scabies in the Nata catchment area was noted to be high. The risk factors included younger age, a household member with an itch, and less frequent bathing. Prospective studies are needed to explore household disease transmission dynamics and risk factors specific to the youth.
摘要：
背景：对sc疮的流行病学了解甚少，特别是在疾病负担较高的地区。缺乏流行病学数据，尤其是在撒哈拉以南非洲，妨碍了控制和预防措施。这项研究旨在估计Tutume区Nata和Sowa集水区的of疮和脓疱病的患病率和相关危险因素。
方法：在Tutume区进行了一项横断面研究，瞄准Manxhotae的定居点，Malelejwe,Ndutshaa,还有Tshwaane.参与者是从定居点的家庭中随机选择的。使用问卷收集数据，并且如果参与者符合国际sca病控制联盟(IACS)共识标准的标准B和或C,则将其归类为sc疮典型病变.统计显著性设定为p<0.05,精确度为95%置信区间。
结果：共有429名参与者被纳入四个定居点。sc疮的总体患病率为18.18％（95CI14.8-22.1）。the疮的患病率最高的是Manxhotae，为27.1％（95CI21.2-34.0）和Ndutshaa，为23.4％（95CI13.4-37.3）。Malelejwe和Tshwaane的患病率较低，分别为10.4％（95CI6.2-16.8）和3.4％（95CI0.8-12.7），分别。仅发现五（5）例脓疱病。多变量logistic回归分析显示，年龄0-4岁，5-18岁和一个有瘙痒的家庭成员与sc疮密切相关，调整后的优势比（AOR）为7.9（95CI2.4-25.6）p值0.001，5.7（95CI2.7-11.7），p值0.001和14.3(95CI5.3-38.5)p值分别为0.001。
结论：注意到Nata集水区sc疮的患病率很高。风险因素包括年龄较小，一个发痒的家庭成员，很少洗澡。需要进行前瞻性研究，以探索年轻人特有的家庭疾病传播动态和风险因素。
方法：在Tutume区进行了一项横断面研究，瞄准Manxhotae的定居点，Malelejwe,Ndutshaa,还有Tshwaane.参与者是从定居点的家庭中随机选择的。使用问卷收集数据，并且如果参与者符合国际sca病控制联盟(IACS)共识标准的标准B和或C,则将其归类为sc疮典型病变.统计显著性设定为p<0.05,精确度为95%置信区间。
结果：共有429名参与者被纳入四个定居点。sc疮的总体患病率为18.18％（95CI14.8-22.1）。the疮的患病率最高的是Manxhotae，为27.1％（95CI21.2-34.0）和Ndutshaa，为23.4％（95CI13.4-37.3）。Malelejwe和Tshwaane的患病率较低，分别为10.4％（95CI6.2-16.8）和3.4％（95CI0.8-12.7），分别。仅发现五（5）例脓疱病。多变量logistic回归分析显示，年龄0-4岁，5-18岁和一个有瘙痒的家庭成员与sc疮密切相关，调整后的优势比（AOR）为7.9（95CI2.4-25.6）p值0.001，5.7（95CI2.7-11.7），p值0.001和14.3(95CI5.3-38.5)p值分别为0.001。
结论：注意到Nata集水区sc疮的患病率很高。风险因素包括年龄较小，一个发痒的家庭成员，很少洗澡。需要进行前瞻性研究，以探索年轻人特有的家庭疾病传播动态和风险因素。
