Abstract：
Mpox is a zoonotic disease that became epidemic in multiple countries in 2022. There is a lack of published systematic reviews on natural animal infection due to Mpox. We performed a systematic literature review with meta-analysis to assess animal Mpox prevalence. We performed a random-effects model meta-analysis to calculate the pooled prevalence and 95% confidence interval (95%CI) for prevalence studies. After the screening, 15 reports were selected for full-text assessment and included in qualitative and quantitative analyses. Ten reports assessed Mpox infection by molecular or serological tests (n = 2680), yielding a pooled prevalence of 16.0% (95%CI: 3.0-29.0%) for non-human primates; 8.0% (95%CI: 4.0-12.0%) for rodents and 1.0% (95%CI: 0.0-3.0%) for shrews. Further studies in other animals are required to define the extent and importance of natural infection due to Mpox. These findings have implications for public human and animal health. OneHealth approach is critical for prevention and control.
摘要：
水痘是一种人畜共患疾病，2022年在多个国家流行。缺乏关于水痘引起的自然动物感染的系统评价。我们进行了系统的文献综述和荟萃分析，以评估动物水痘的患病率。我们进行了随机效应模型荟萃分析，以计算患病率研究的合并患病率和95％置信区间（95CI）。筛选后,选择了15份报告进行全文评估，并纳入定性和定量分析。十份报告通过分子或血清学测试评估了水痘感染（n=2680），非人类灵长类动物的合并患病率为16.0％（95CI：3.0-29.0％）;啮齿动物为8.0％（95CI：4.0-12.0％），sh为1.0％（95CI：0.0-3.0％）。需要在其他动物中进行进一步的研究，以确定由于水痘引起的自然感染的程度和重要性。这些发现对公众人类和动物健康有影响。OneHealth方法对于预防和控制至关重要。
