关键词: Intracranial teratoma Paraneoplastic syndrome Vasospasm

Mesh : Humans Teratoma / complications surgery diagnostic imaging Brain Neoplasms / complications diagnostic imaging Vasospasm, Intracranial / etiology diagnostic imaging Stroke / etiology diagnostic imaging complications Paraneoplastic Syndromes Male Child Female

来  源:   DOI:10.1007/s00381-024-06471-z

Abstract:
Teratomas account for 18-20% of all intracranial germ cell tumors and mostly occur in the pineal region with only a few cases of pediatric sellar and suprasellar teratomas described in the literature. Here, we present a case of a child with an intracranial mature teratoma with pancreatic features causing vasospasm and subsequent stroke, found to be positive for CDKN2A-an independent variant associated with malignancy and small vessel disease leading to stroke.
摘要:
畸胎瘤占所有颅内生殖细胞肿瘤的18-20%,主要发生在松果体区域,文献中描述的小儿鞍和鞍上畸胎瘤只有少数病例。这里,我们介绍了一例患有颅内成熟畸胎瘤的儿童,其胰腺特征导致血管痉挛和随后的中风,发现CDKN2A阳性-与恶性肿瘤和小血管疾病相关的独立变异导致卒中。
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