PDF(Pubmed)
Abstract：
UNASSIGNED: To evaluate the efficacy and safety of Holmium: Yttrium-Aluminum-Garnet (Ho:YAG) laser in bladder lithotripsy using high-power settings > 100 W.
UNASSIGNED: A combined experimental and clinical study was conducted. The Quanta Cyber: Ho 150 with a 550 μm Quanta optical fiber was utilized in all set-ups. Ablation rates for soft and hard artificial stones were tested in vitro using 100 W and 20 W power settings. In the experiment, a porcine bladder was used. The optical fiber was inserted through a rigid cystoscope, whilst a K-type thermocouple was inserted in the bladder dome. The tested high-power settings were 152 W, 120 W and 105 W. In every trial, the lasing time was over 60 s. In the clinical study, 35 patients underwent transurethral high-power bladder lithotripsy. Laser settings were set between 100 W and 150 W.
UNASSIGNED: Stone mass (stone weight) was significantly lower after stone ablation independently of the stone type or the laser settings. Significantly higher mass decrease and ablation rate were detected in high-power compared to low-power settings. In the experiment, the highest temperature recorded was 32°C at 152 W. At 120 W and 105 W, the peak temperatures didn\'t reach 30°C. In the clinical study, a stone-free rate of 100% and a mean operative time of 43 ± 18 min were reported. All patients stayed in the hospital for one day except for one who presented minor hematuria. Additional complications did not occur.
UNASSIGNED: Ho:YAG laser lithotripsy > 100 W is an effective, fast and safe modality for the treatment of bladder calculi.
UNASSIGNED: A combined experimental and clinical study was conducted. The Quanta Cyber: Ho 150 with a 550 μm Quanta optical fiber was utilized in all set-ups. Ablation rates for soft and hard artificial stones were tested in vitro using 100 W and 20 W power settings. In the experiment, a porcine bladder was used. The optical fiber was inserted through a rigid cystoscope, whilst a K-type thermocouple was inserted in the bladder dome. The tested high-power settings were 152 W, 120 W and 105 W. In every trial, the lasing time was over 60 s. In the clinical study, 35 patients underwent transurethral high-power bladder lithotripsy. Laser settings were set between 100 W and 150 W.
UNASSIGNED: Stone mass (stone weight) was significantly lower after stone ablation independently of the stone type or the laser settings. Significantly higher mass decrease and ablation rate were detected in high-power compared to low-power settings. In the experiment, the highest temperature recorded was 32°C at 152 W. At 120 W and 105 W, the peak temperatures didn\'t reach 30°C. In the clinical study, a stone-free rate of 100% and a mean operative time of 43 ± 18 min were reported. All patients stayed in the hospital for one day except for one who presented minor hematuria. Additional complications did not occur.
UNASSIGNED: Ho:YAG laser lithotripsy > 100 W is an effective, fast and safe modality for the treatment of bladder calculi.
摘要：
■为了评估钬：钇-铝-石榴石（Ho：YAG）激光在高功率设置>100W的膀胱碎石术中的疗效和安全性。
■进行了一项联合实验和临床研究。在所有设置中都使用了具有550μmQuanta光纤的QuantaCyber：Ho150。使用100W和20W的功率设置在体外测试了软和硬人造石的消融率。在实验中,使用猪膀胱。光纤通过刚性膀胱镜插入，同时将K型热电偶插入膀胱圆顶中。测试的高功率设置为152W，120瓦和105瓦在每次试验中，激光时间超过60秒。在临床研究中，35例患者接受经尿道高功率膀胱碎石术。激光设置设置在100W和150W之间。
■石块消融后，石块质量（石块重量）明显较低，与石块类型或激光设置无关。与低功率设置相比，在高功率设置中检测到明显更高的质量减少和消融速率。在实验中,记录的最高温度为32°C，温度为152W。在120W和105W时，峰值温度没有达到30°C。在临床研究中,据报道，结石清除率为100％，平均手术时间为43±18分钟。除一名患者出现轻微血尿外，所有患者均在医院住院一天。没有发生其他并发症。
■Ho:YAG激光碎石术>100W是有效的，快速和安全的方式治疗膀胱结石。
■进行了一项联合实验和临床研究。在所有设置中都使用了具有550μmQuanta光纤的QuantaCyber：Ho150。使用100W和20W的功率设置在体外测试了软和硬人造石的消融率。在实验中,使用猪膀胱。光纤通过刚性膀胱镜插入，同时将K型热电偶插入膀胱圆顶中。测试的高功率设置为152W，120瓦和105瓦在每次试验中，激光时间超过60秒。在临床研究中，35例患者接受经尿道高功率膀胱碎石术。激光设置设置在100W和150W之间。
■石块消融后，石块质量（石块重量）明显较低，与石块类型或激光设置无关。与低功率设置相比，在高功率设置中检测到明显更高的质量减少和消融速率。在实验中,记录的最高温度为32°C，温度为152W。在120W和105W时，峰值温度没有达到30°C。在临床研究中,据报道，结石清除率为100％，平均手术时间为43±18分钟。除一名患者出现轻微血尿外，所有患者均在医院住院一天。没有发生其他并发症。
■Ho:YAG激光碎石术>100W是有效的，快速和安全的方式治疗膀胱结石。
