{Reference Type}: Journal Article
{Title}: High-power Holmium:Yag lithotripsy in bladder urolithiasis: Is it safe and effective? A combined clinical and experimental study.
{Author}: Pagonis K;Katsakiori P;Peteinaris A;Tatanis V;Tsaturyan A;Faria Costa G;Faitatziadis S;Vagionis A;Natsos A;Gkeka K;Obaidat M;Spinos T;Vrettos T;Liatsikos E;Kallidonis P;
{Journal}: Arab J Urol
{Volume}: 22
{Issue}: 3
{Year}: 2024
暂无{DOI}: 10.1080/20905998.2024.2304516
{Abstract}: <B>UNASSIGNED: </B>To evaluate the efficacy and safety of Holmium: Yttrium-Aluminum-Garnet (Ho:YAG) laser in bladder lithotripsy using high-power settings > 100 W.<BR><B>UNASSIGNED: </B>A combined experimental and clinical study was conducted. The Quanta Cyber: Ho 150 with a 550 μm Quanta optical fiber was utilized in all set-ups. Ablation rates for soft and hard artificial stones were tested in vitro using 100 W and 20 W power settings. In the experiment, a porcine bladder was used. The optical fiber was inserted through a rigid cystoscope, whilst a K-type thermocouple was inserted in the bladder dome. The tested high-power settings were 152 W, 120 W and 105 W. In every trial, the lasing time was over 60 s. In the clinical study, 35 patients underwent transurethral high-power bladder lithotripsy. Laser settings were set between 100 W and 150 W.<BR><B>UNASSIGNED: </B>Stone mass (stone weight) was significantly lower after stone ablation independently of the stone type or the laser settings. Significantly higher mass decrease and ablation rate were detected in high-power compared to low-power settings. In the experiment, the highest temperature recorded was 32°C at 152 W. At 120 W and 105 W, the peak temperatures didn't reach 30°C. In the clinical study, a stone-free rate of 100% and a mean operative time of 43 ± 18 min were reported. All patients stayed in the hospital for one day except for one who presented minor hematuria. Additional complications did not occur.<BR><B>UNASSIGNED: </B>Ho:YAG laser lithotripsy > 100 W is an effective, fast and safe modality for the treatment of bladder calculi.