Abstract：
Calcium is a crucial second messenger in the cell that is stored in organelles including lysosomes. Proteins that facilitate calcium entry to the lysosome were unknown. A recent report by Zajac et al. identified TMEM165 as a proton-activated calcium importer on the lysosome, thus discovering a key player in subcellular calcium homeostasis.
摘要：
钙是细胞中重要的第二信使，储存在包括溶酶体在内的细胞器中。促进钙进入溶酶体的蛋白质是未知的。Zajac等人最近的一份报告。将TMEM165鉴定为溶酶体上的质子活化钙导入体，从而发现亚细胞钙稳态的关键角色。
