%0 Journal Article
%T Sharing is caring: TMEM165 a Golgi calcium importer used by the lysosome.
%A Murchison AK
%A Abu-Remaileh M
%J Trends Biochem Sci
%V 49
%N 8
%D 2024 Aug 29
%M 38816278
%F 14.264
%R 10.1016/j.tibs.2024.05.006
%X Calcium is a crucial second messenger in the cell that is stored in organelles including lysosomes. Proteins that facilitate calcium entry to the lysosome were unknown. A recent report by Zajac et al. identified TMEM165 as a proton-activated calcium importer on the lysosome, thus discovering a key player in subcellular calcium homeostasis.