METHODS: The subjects were 10 healthy volunteers aged 22-60 years. MRI models with 3 Tesla strength from five different companies were used. Cartilage thickness was quantified fully automatically for seven regions. We hypothesized that \"the MRI model influences cartilage thickness measurements.\" Inter-measurement error, defined as the absolute difference between the targeted and median thicknesses determined by the five MRI models, was analyzed using histograms. The factors generating the largest inter-measurement error were also examined.
RESULTS: No exceptional trends attributable to a specific instrument model were observed, and the p-value from the Kruskal-Wallis test exceeded 0.05 in all seven regions. Therefore, the study hypothesis was rejected. Of the 350 measurements, the inter-measurement error was ≤0.05 mm in 53 %, ≤0.10 mm in 75 %, and ≤0.20 mm in 95 %. Analysis of the medial tibial cartilage, which had the largest inter-measurement error, revealed mis-extraction of synovial fluid as cartilage.
CONCLUSIONS: The choice of MRI model did not influence cartilage thickness measurements. Overall, 95 % of the inter-measurement errors were within 0.20 mm. The greatest error resulted from mis-extracting synovial fluid as cartilage.
方法:受试者为10名健康志愿者,年龄22~60岁。使用了来自五家不同公司的具有3特斯拉强度的MRI模型。对于七个区域全自动定量软骨厚度。我们假设MRI模型影响软骨厚度测量。“相互测量误差,定义为由五个MRI模型确定的目标厚度和中值厚度之间的绝对差异,使用直方图进行了分析。还检查了产生最大测量间误差的因素。
结果:没有观察到归因于特定仪器型号的异常趋势,在所有七个区域中,Kruskal-Wallis检验的p值超过0.05。因此,研究假设被拒绝.在350次测量中,测量间误差≤0.05mm,为53%,在75%中≤0.10mm,95%≤0.20mm。胫骨内侧软骨的分析,具有最大的测量间误差,显示滑液作为软骨的错误提取。
结论:MRI模型的选择不影响软骨厚度测量。总的来说,95%的测量间误差在0.20mm以内。最大的误差是由于误提取滑液作为软骨。