Abstract：
UNASSIGNED: Antimicrobial drugs form an essential component of medical treatment in human and animal health. Resistance associated with their use has posed a global public health threat. Multiple efforts have been made at the global level directed by the World Health Organization and associated partners to develop policies aimed at combatting antimicrobial resistance.
UNASSIGNED: Whilst the Global Action Plan on antimicrobial resistance and people-centered framework aim to guide countries in implementing successful antimicrobial resistance policies, their adoption and success depend on different implementation contexts. Therefore, this paper highlights the challenges and opportunities for implementing the World Health Organization\'s people-centered approach in sub-Saharan Africa, whilst recognizing antimicrobial resistance as a multifaceted problem rooted in \'complex systems.\'
UNASSIGNED: The people-centered approach provides a solid framework for combating antimicrobial resistance. Countries should build sustainable national action plans, adopt the One Health approach, limit over-the-counter antibiotic consumption, and educate communities on rational antibiotic use. They should also promote inter-country collaborations and innovative solutions, strengthen drug regulatory capacities, invest in infection control, water sanitation, hygiene, diagnostics, and surveillance tools, and promote vaccine uptake to prevent drug-resistant infections.
UNASSIGNED: Whilst the Global Action Plan on antimicrobial resistance and people-centered framework aim to guide countries in implementing successful antimicrobial resistance policies, their adoption and success depend on different implementation contexts. Therefore, this paper highlights the challenges and opportunities for implementing the World Health Organization\'s people-centered approach in sub-Saharan Africa, whilst recognizing antimicrobial resistance as a multifaceted problem rooted in \'complex systems.\'
UNASSIGNED: The people-centered approach provides a solid framework for combating antimicrobial resistance. Countries should build sustainable national action plans, adopt the One Health approach, limit over-the-counter antibiotic consumption, and educate communities on rational antibiotic use. They should also promote inter-country collaborations and innovative solutions, strengthen drug regulatory capacities, invest in infection control, water sanitation, hygiene, diagnostics, and surveillance tools, and promote vaccine uptake to prevent drug-resistant infections.
摘要：
抗菌药物是人类和动物健康医学治疗的重要组成部分。与使用它们相关的耐药性已构成全球公共卫生威胁。在世界卫生组织和相关伙伴的指导下，在全球一级做出了多项努力，以制定旨在打击抗微生物药物耐药性的政策。
虽然抗菌素耐药性全球行动计划和以人为本的框架旨在指导各国实施成功的抗菌素耐药性政策，它们的采用和成功取决于不同的实施环境。因此,本文强调了在撒哈拉以南非洲实施世界卫生组织以人为本方法的挑战和机遇，同时认识到抗菌素耐药性是一个根植于复杂系统的多方面问题。\'
■以人为本的方法为对抗抗菌素耐药性提供了坚实的框架。各国应制定可持续的国家行动计划，采用一个健康的方法，限制非处方抗生素消费，并教育社区合理使用抗生素。它们还应促进国家间合作和创新解决方案，加强药品监管能力，投资于感染控制，水卫生,卫生,诊断,和监视工具,并促进疫苗接种以预防耐药感染。
虽然抗菌素耐药性全球行动计划和以人为本的框架旨在指导各国实施成功的抗菌素耐药性政策，它们的采用和成功取决于不同的实施环境。因此,本文强调了在撒哈拉以南非洲实施世界卫生组织以人为本方法的挑战和机遇，同时认识到抗菌素耐药性是一个根植于复杂系统的多方面问题。\'
■以人为本的方法为对抗抗菌素耐药性提供了坚实的框架。各国应制定可持续的国家行动计划，采用一个健康的方法，限制非处方抗生素消费，并教育社区合理使用抗生素。它们还应促进国家间合作和创新解决方案，加强药品监管能力，投资于感染控制，水卫生,卫生,诊断,和监视工具,并促进疫苗接种以预防耐药感染。
