PDF(Pubmed)
Abstract：
OBJECTIVE: Periodontitis is an inflammatory condition induced by subgingival bacterial dysbiosis, resulting in inflammatory-mediated destruction of tooth-supporting structures, potentially leading to the formation of infrabony defects. This case report describes the treatment of a patient who presented with a combination 1-2-wall defect on tooth 21. To maintain the residual periodontal attachment and minimize esthetic consequences, a regenerative approach was performed using recombinant human platelet-derived growth factor-BB (rh-PDGF-BB) and β-tricalcium phosphate (β-TCP).
METHODS: At the time of postscaling/root planing reevaluation, a 34-year-old Asian male initially diagnosed with molar/incisor pattern stage III grade C periodontitis exhibited a 6-mm residual probing depth on the mesiopalatal aspect of tooth 21. Periodontal regenerative surgery was performed using rh-PDGF-BB with β-TCP, without the use of a membrane.
RESULTS: At the 1-year follow-up, a significant reduction in probing depth and radiographic evidence of bone fill were observed. Additionally, re-entry surgery for implant placement at site tooth 23 confirmed bone fill in the defect on tooth 21.
CONCLUSIONS: These results demonstrate the efficacy of rh-PDGF-BB with β-TCP in enhancing periodontal regeneration and support its use as a treatment option when treating poorly contained infrabony defects in the esthetic zone.
METHODS: At the time of postscaling/root planing reevaluation, a 34-year-old Asian male initially diagnosed with molar/incisor pattern stage III grade C periodontitis exhibited a 6-mm residual probing depth on the mesiopalatal aspect of tooth 21. Periodontal regenerative surgery was performed using rh-PDGF-BB with β-TCP, without the use of a membrane.
RESULTS: At the 1-year follow-up, a significant reduction in probing depth and radiographic evidence of bone fill were observed. Additionally, re-entry surgery for implant placement at site tooth 23 confirmed bone fill in the defect on tooth 21.
CONCLUSIONS: These results demonstrate the efficacy of rh-PDGF-BB with β-TCP in enhancing periodontal regeneration and support its use as a treatment option when treating poorly contained infrabony defects in the esthetic zone.
摘要：
目的：牙周炎是由牙龈下细菌菌群失调引起的炎症，导致炎症介导的牙齿支撑结构的破坏，可能导致形成侵权缺陷。该病例报告描述了在牙齿21上出现1-2壁组合缺损的患者的治疗。为了保持残留的牙周附着并最大程度地减少美学后果，使用重组人血小板衍生生长因子-BB（rh-PDGF-BB）和β-磷酸三钙（β-TCP）进行再生方法。
方法：在缩放后/根面规划重新评估时，一名34岁的亚洲男性最初被诊断为磨牙/切牙模式III期C级牙周炎，在21颗牙齿的近泪层方面显示出6毫米的残留探查深度。使用rh-PDGF-BB和β-TCP进行牙周再生手术，不使用膜。
结果：在1年的随访中，观察到探测深度和骨填充的影像学证据显著减少.此外,用于在部位牙齿23处放置植入物的重新进入手术证实了牙齿21上的缺损中的骨填充。
结论：这些结果证明了rh-PDGF-BB与β-TCP在增强牙周再生方面的功效，并支持将其用作治疗美学区域中不含缺陷缺陷的治疗选择。
方法：在缩放后/根面规划重新评估时，一名34岁的亚洲男性最初被诊断为磨牙/切牙模式III期C级牙周炎，在21颗牙齿的近泪层方面显示出6毫米的残留探查深度。使用rh-PDGF-BB和β-TCP进行牙周再生手术，不使用膜。
结果：在1年的随访中，观察到探测深度和骨填充的影像学证据显著减少.此外,用于在部位牙齿23处放置植入物的重新进入手术证实了牙齿21上的缺损中的骨填充。
结论：这些结果证明了rh-PDGF-BB与β-TCP在增强牙周再生方面的功效，并支持将其用作治疗美学区域中不含缺陷缺陷的治疗选择。
