Abstract：
Solanum glaucophyllum is a toxic plant with calcinogenic effect that causes enzootic calcinosis (EC) characterized by soft tissue metastatic mineralization mainly in cattle and rarely sheep, buffaloes, pigs, horses, and goats. We describe an outbreak of EC in a herd of 64 goats due to S. glaucophyllum consumption. Thirty-four goats were affected exhibiting hirsutism, stiffening, kyphosis and emaciation. Twelve goats died. Grossly, tissue mineralization was observed in the aorta and carotid arteries, lungs, and heart. Lesions were characterized by multiple rough white plaques, and hardened tissues with loss of elasticity. Microscopically, multisystemic mineralization was observed in aorta and carotid arteries, heart, lung, abomasum, intestine, spleen, lymph nodes, kidney, spleen, and meninges, characterized by extensive granular basophilic deposits of tunica media and/or intima of blood vessels; confirmed as calcium salt deposits with Von Kossa stain. We conclude that ingestion of S. glaucophyllum can cause EC in goats. Though EC is rare in goats under some conditions such as heavy drought and abundant S. glaucophyllum exposure disease can develop.
摘要：
龙葵是一种具有钙质作用的有毒植物，可引起植物性钙质沉着症（EC），其特征是主要在牛和很少在绵羊中的软组织转移性矿化。水牛,猪,马,还有山羊.我们描述了由于食用芒草而导致的64只山羊中EC的爆发。三十四只山羊受到影响，表现出多毛症，加劲,后凸和消瘦。十二只山羊死亡。严重的,在主动脉和颈动脉中观察到组织矿化，肺,和心脏。病变以多个粗糙的白色斑块为特征，和硬化组织失去弹性。微观上,在主动脉和颈动脉中观察到多系统矿化，心,肺，皱胃,肠,脾,脾淋巴结,肾,脾,脾和脑膜，以中膜和/或血管内膜的大量颗粒状嗜碱性沉积物为特征；经VonKossa染色证实为钙盐沉积物。我们得出的结论是，摄入芒草可导致山羊的EC。尽管在某些条件下，例如严重的干旱和大量的芒硝暴露病，山羊中的EC很少见。
