PDF(Pubmed)
Abstract：
Gastric cancer (GC) remains a significant global health concern, ranking as the third leading cause of cancer-related deaths. Malnutrition is common in GC patients and can negatively impact prognosis and quality of life. Understanding nutritional issues and their management is crucial for improving patient outcomes. This cross-sectional study included 51 GC patients who underwent curative surgery, either total or subtotal gastrectomy. Various nutritional assessments were conducted, including anthropometric measurements, laboratory tests, and scoring systems such as Eastern Cooperative Oncology Group/World Health Organization Performance Status (ECOG/WHO PS), Observer-Reported Dysphagia (ORD), Nutritional Risk Screening-2002 (NRS-2002), Patient-Generated Subjective Global Assessment (PG-SGA), and Simplified Nutritional Appetite Questionnaire (SNAQ). Serum carcinoembryonic antigen (CEA) levels were significantly higher in the subtotal gastrectomy group. Nutritional assessments indicated a higher risk of malnutrition in patients who underwent total gastrectomy, as evidenced by higher scores on ORD, NRS-2002, and PG-SGA. While total gastrectomy was associated with a higher risk of malnutrition, no single nutritional parameter emerged as a strong predictor of surgical approach. PG-SGA predominantly identified malnutrition, with its occurrence linked to demographic factors such as female gender and age exceeding 65 years.
摘要：
胃癌（GC）仍然是一个重要的全球健康问题，排名第三的癌症相关死亡原因。营养不良在GC患者中很常见，会对预后和生活质量产生负面影响。了解营养问题及其管理对于改善患者预后至关重要。这项横断面研究包括51例接受治愈性手术的GC患者，全胃切除术或次全胃切除术。进行了各种营养评估，包括人体测量,实验室测试,和评分系统，如东部肿瘤学合作小组/世界卫生组织绩效状况(ECOG/WHOPS)，观察者报告的吞咽困难（ORD），营养风险筛查-2002(NRS-2002)，患者主观整体评估(PG-SGA)和简化营养食欲问卷(SNAQ)。胃大部切除术组血清癌胚抗原（CEA）水平明显升高。营养评估表明，接受全胃切除术的患者营养不良的风险更高。ORD的更高分数证明了这一点，NRS-2002和PG-SGA。虽然全胃切除术与较高的营养不良风险相关，没有单一的营养参数作为手术入路的强预测指标出现.PG-SGA主要确定营养不良，其发生与人口因素有关，如女性性别和年龄超过65岁。
